ul_4151----
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PPBD protein
Gene name PIK3R1( Description: coilin. )
Synonyms CLN80; PI3-kinase p85 subunit alpha; PI3K; PtdIns-3-kinase p85-alpha; p80-coilin; p85a
GO annotations GO_component: intracellular; phosphoinositide 3-kinase complex; phosphoinositide 3-kinase complex, class IA
GO_function:ErbB-3 class receptor binding [PMID 10572067]; insulin binding [PMID 8440175]; insulin receptor binding [PMID 7537849] [PMID 8276809]; insulin receptor substrate binding; insulin-like growth factor receptor binding [PMID 7541045]; kinase activity; phosphatidylinositol binding; phosphoinositide 3-kinase regulator activity; protein phosphatase binding [PMID 14699157]
GO_process: insulin receptor signaling pathway [PMID 8276809]; insulin-like growth factor receptor signaling pathway [PMID 7541045]; intracellular signaling cascade; phosphoinositide phosphorylation
RefSeq accession NP_852556
SwissProt accession P27986
Substrate protein
Gene name Mycs( Description: myc-like oncogene, s-myc protein. )
Synonyms
GO annotations GO_component:
GO_function:
GO_process: apoptosis
RefSeq accession NP_068609
SwissProt accession
Sequence:(RefSeq accession:NP_068609; substrate region highlighted if known)
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MLSCTTSTMP GMICKNSDLE FDSLKPCFYP EDDDIYFGGR NSTPPGEDIW KKFELLPTPR
LSPGRALAED SLEPANWATE MLLPEADLWS NPAEEEDIFG LKGLSGSSSN PVVLQDCMWS
GFSSREKPET VVSEKLPGGC GSLAVGAGTL VPGAAAATSA GHARSGTAGV GRRKAAWLTE
LSHLDSECVD SAVIFPANKR ESMPVATIPA SAGAAISLGD HQGLSSSLED FLSNSGYVEE
GGEEIYVVML GETQFSKTVT KLPTAAHSEN AALTPECAQS GELILKRSDL IQEQHNYAAP
PLPYAEDARP LKKPRSQDPL GPLKCVLRPK APRLRSRSNS DLEDIERRRN HNRMERQRRD
IMRSSFLNLR DLVPELVHNE KAAKVVILKK ATEYIHTLQT DESKLLVERE KLYERKQQLL
EKIKQSAVC
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, et al., SH2 domains recognize specific phosphopeptide sequences, [7680959]
End of Record Details