ul_4196----
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PPBD protein
Gene name PIK3R1( Description: coilin. )
Synonyms CLN80; PI3-kinase p85 subunit alpha; PI3K; PtdIns-3-kinase p85-alpha; p80-coilin; p85a
GO annotations GO_component: intracellular; phosphoinositide 3-kinase complex; phosphoinositide 3-kinase complex, class IA
GO_function:ErbB-3 class receptor binding [PMID 10572067]; insulin binding [PMID 8440175]; insulin receptor binding [PMID 7537849] [PMID 8276809]; insulin receptor substrate binding; insulin-like growth factor receptor binding [PMID 7541045]; kinase activity; phosphatidylinositol binding; phosphoinositide 3-kinase regulator activity; protein phosphatase binding [PMID 14699157]
GO_process: insulin receptor signaling pathway [PMID 8276809]; insulin-like growth factor receptor signaling pathway [PMID 7541045]; intracellular signaling cascade; phosphoinositide phosphorylation
RefSeq accession NP_852556
SwissProt accession P27986
Substrate protein
Gene name unc-104( Description: UNCoordinated. )
Synonyms
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_741019
SwissProt accession
Sequence:(RefSeq accession:NP_741019; substrate region highlighted if known)
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MSSVKVAVRV RPFNQREISN TSKCVLQVNG NTTTINGHSI NKENFSFNFD HSYWSFARND
PHFITQKQVY EELGVEMLEH AFEGYNVCIF AYGQTGSGKS YTMMGKANDP DEMGIIPRLC
NDLFARIDNN NDKDVQYSVE VSYMEIYCER VKDLLNPNSG GNLRVREHPL LGPYVDDLTK
MAVCSYHDIC NLMDEGNKAR TVAATNMNST SSRSHAVFTI VLTQKRHCAD SNLDTEKHSK
ISLVDLAGSE RANSTGAEGQ RLKEGANINK SLTTLGLVIS KLAEESTKKK KSNKGVIPYR
DSVLTWLLRE NLGGNSKTAM LAALSPADIN FDETLSTLRY ADRAKQIVCQ AVVNEDPNAK
LIRELNEEVI KLRHILKDKG IDVTDVQETP GKHKKGPKLP AHVHEQLEKL QESEKLMAEI
GKTWEQKLIH TEEIRKQREE ELRDMGLACA EDGTTLGVFS PKKLPHLVNL NEDPLMSECL
IYYLKEGVTS VGRPVAEHRP DILLSGEAIL ELHCEFINED GNVTLTMKPN ASCYINGKQV
TTPTVLHTGS RVILGEHHVF RYNDPQEARQ SRHNLAAIAE QPIDWKYAQQ ELLDKQGIDL
KADMEKKMLE MESQYRREKV ELEQKMYHQT REYESMIENL QKQVDLAQSY ISGGGSIWEG
ERMLTSSLLE FPEELKWTSD QKRVVLKAAI KWRYHQFTSV RDDLWGNAIF VKEANAISVE
LKKKVQFQFA LLTDTMYSPL PPDLLPPGED LTLRPYPKTV VAIQVQDLKN GATHYWSIEK
LKQRLEAMRD MYETDAEMSP ADGDPMMDAL MGTDPFYDRF PWFRMVGRAF VYLNNLLHNV
PLIHKVAVVN EKGEVKGYLK VAIEPVQKDE VINQKKGVRQ TAKLHFRKED FLKSHKNGET
SDSDALAFPE HMQEEVEFCF RVVVLQAIDV ADTYSDVFCQ FNFLHRHDEA FSTEPMKNSK
SPLTFEHTQN LHIKMSKTFL HYLHHFPIIF EVFGHFQPKS EQFNFERQNS ALGRRLSTKL
TFQQPSLVIS TPVKSKKANA PIQNNNASVK SKHDLLVWFE ICELANNGEY VPTIVDHAQG
LPTHGIFLLH QGIQRRIKIT ICHEKGELKW KDCQELVVGR IRAGPEWAGG DDVDVLSLGL
FPGTFMEFSM DDRTFFQFEA AWDSSLHNSP LLNRVSNYGD QIYMTLSAYM ELDGCAQPAV
VTKDLCLLIY ARDSKISAAS RFCRSLVGGI SKSPEMNRVP GVYQLCLKDG SDSGSPGAIR
RQRRVLDTSS AYVRGEENLG QWRPRGDSLI FEHQWELEKL TRLQQVERVR LFLRLRDRLK
GKKNKGEART PVSPCDPVCA IPESIKLDEK DKGIVGKVLG LIRRKIPMNK DPPTGNKAQE
LSDESGSNSI TSPVSDKSLI KSSRSSDLLC RQKSKSDQNL ASNDDIVDNL GGMKRSLSGS
RILQLNILVP EVLEERVGVV VSKKGYMNFL EEKTQGWTRR WVIVRRPYIL LFRDDRDLVI
RGIINLANAR IEHSEDQQAM VKVPNTFSVC TNQRGFLMQM MPGDEMYDWL YAINPLMAGQ
MKLHGNQNGT TLKSPTSSSS IAAS
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, et al., SH2 domains recognize specific phosphopeptide sequences, [7680959]
End of Record Details