ul_4541----
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PPBD protein
Gene name PIK3R1
Synonyms PI3-kinase p85 subunit alpha; PI3K; PtdIns-3-kinase p85-alpha; p85a
GO annotations GO_component: intracellular; phosphoinositide 3-kinase complex; phosphoinositide 3-kinase complex, class IA
GO_function:ErbB-3 class receptor binding [PMID 10572067]; insulin binding [PMID 8440175]; insulin receptor binding [PMID 7537849] [PMID 8276809]; insulin receptor substrate binding; insulin-like growth factor receptor binding [PMID 7541045]; kinase activity; phosphatidylinositol binding; phosphoinositide 3-kinase regulator activity; protein phosphatase binding [PMID 14699157]
GO_process: insulin receptor signaling pathway [PMID 8276809]; insulin-like growth factor receptor signaling pathway [PMID 7541045]; intracellular signaling cascade; phosphoinositide phosphorylation
RefSeq accession NP_852664
SwissProt accession P27986
Substrate protein
Gene name XMRK_XIPMA( Description: Tir. )
Synonyms 2.3; 34Ea; BG:DS00941.4; CG10637; CG18250; CG6772; CG7793; CG8200; CK02126; CT41273; DG; DmDG; E(sev)2A; EK2-8; EY2-3; FLO1; FLO[Dm]; RPB1; RPB220; SOS; SUA8; Sos1; Su(tor)2-2; YAP2; br24; br25; d; dSos; dgn; dme-SOS; l(2)34Ea; l(2)br24; l(2)br25; l(2)k05224; l(2)k06321; nak; reggie-2; slob
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession
SwissProt accession P13388
GO Pathway:
GO:0043066     negative regulation of apoptosis
Sequence:(RefSeq accession:; substrate region highlighted if known)
Records:
Category Evidence Reference
A Peptide library Wellbrock C, Fischer P, Schartl M., PI3-kinase is involved in mitogenic signaling by the oncogenic receptor tyrosine kinase Xiphophorus melanoma receptor kinase in fish melanoma, [10471319]
End of Record Details