ul_4564----
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PPBD protein
Gene name PIK3R1
Synonyms PI3-kinase p85 subunit alpha; PI3K; PtdIns-3-kinase p85-alpha; p85a
GO annotations GO_component: intracellular; phosphoinositide 3-kinase complex; phosphoinositide 3-kinase complex, class IA
GO_function:ErbB-3 class receptor binding [PMID 10572067]; insulin binding [PMID 8440175]; insulin receptor binding [PMID 7537849] [PMID 8276809]; insulin receptor substrate binding; insulin-like growth factor receptor binding [PMID 7541045]; kinase activity; phosphatidylinositol binding; phosphoinositide 3-kinase regulator activity; protein phosphatase binding [PMID 14699157]
GO_process: insulin receptor signaling pathway [PMID 8276809]; insulin-like growth factor receptor signaling pathway [PMID 7541045]; intracellular signaling cascade; phosphoinositide phosphorylation
RefSeq accession NP_852664
SwissProt accession P27986
Substrate protein
Gene name dos( Description: daughter of sevenless. )
Synonyms 141511_at; CG1044; DOS; E(csw)3A; E(csw[CS])3A; Su(sev)3A; Su(sev[S11])3A
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_523890
SwissProt accession
Sequence:(RefSeq accession:NP_523890; substrate region highlighted if known)
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MDRTFYEGWL IKSPPTKRIW RARWRRRYFT LKQGEIPEQF CLEYYTDHNC RKLKGVIDLD
QCEQVDCGLR LENRKQKFQY MFDIKTPKRT YYLAAETEAD MRDWVNCICQ VCHLHDTKQS
NELPLGAVGA DENRTQHTSS SGGLSNSTQN TTTTSLHSSA GTTAPQASVP NAGGSAQLRR
PAVIEEQPMP SNAGNNNSDS VYVNTEYSNR ETMLCDANFD QQELLSAAQQ QPPPSPATAL
YLNHSALIQA QAAAAAAEQL QQQQQQAARL AVSANGVVRK LPEHLVLTQQ TLAEAAAQQH
SSVQASPALS TASGPYIPIS ECFSGSPRFL PGVPLPGADL AIPNNPTTPL NNLDPKFYDT
PRSHNNIGLN LTNDQSYSPK ITNLSLQQLA NNNASKQRSD SDSESVFTDD DEWAHPLPLR
ENVDRSTRPS DSSIENESFV LTYSQRFSKM PEEGGAIVPP AEKSSKLAGA ASLPEAGDQG
TLDKLAKVLK NKNNLILDFK ENEKIPRDLP QLSDTENTSP AIVARRNAHS AFIEESYDIP
RSHQQPYYNV NQLLGERPVT SPHNSNPIAA STPNLMAADL GAVAAISAAA NPGLMGEAQA
VASSPTSART LPRHCYTNAA PTKMEGNVFR YDFMEQADCP PVNRKLKPKV AGGLPVVEDK
PPEEFPAKPP VGVDQLTNKL GAAQLQQPIG PPSVDRKCKP NAYKLGNSAT MSPATRRSSG
APLSMVLPHE TDVHSPAAAN AFFHETRTLP RQQHRHHPNS PGSMSVQHQR TASAAAAMMS
LTAAAAPKQQ AAAQTEHKLQ YFDLDVTNKP PLLNRSSMSV GNLYSQGGNG ASGMRFAGVE
AGGARAPVPS SVVYRSVDFV KTEAFKRIRE ERESSGNK
Records:
Category Evidence Reference
A Inference Bausenwein BS, Schmidt M, Mielke B, Raabe T., In vivo functional analysis of the daughter of sevenless protein in receptor tyrosine kinase signaling, [10640704]
End of Record Details