ul_4922----
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PPBD protein
Gene name PLCG1
Synonyms EC 3.1.4.11; PLC-148; PLC-II; PLC-gamma-1; Phosphoinositide phospholipase C; Phospholipase C-gamma-1
GO annotations GO_component:
GO_function:calcium ion binding; hydrolase activity; phosphoinositide phospholipase C activity [PMID 2167438]; protein binding [PMID 10873601] [PMID 14722116]; receptor signaling protein activity [PMID 7681365]; signal transducer activity
GO_process: intracellular signaling cascade; lipid catabolism; lipid metabolism
RefSeq accession NP_002651
SwissProt accession P19174
Substrate protein
Gene name Cd22( Description: CD22 antigen. )
Synonyms A530093D23; Lyb-8; Lyb8
GO annotations GO_component: external side of plasma membrane; integral to plasma membrane; membrane
GO_function:coreceptor activity; protein binding; sugar binding
GO_process: cell adhesion; cell surface receptor linked signal transduction; defense response
RefSeq accession NP_033975
SwissProt accession
Sequence:(RefSeq accession:NP_033975; substrate region highlighted if known)
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MRVHYLWLLL ILGHVASARY SSANDWTVDH PQTLFAWEGA CIRIPCKYKT PLPKARLDNI
LLFQNYEFDK ATKKFTGTVL YNATKTEKDP ESELYLSKQG RVTFLGNRID NCTLKIHPIR
ANDSGNLGLR MTAGTERWME PIHLNVSEKP FQPYIQMPSE IRESQSVTLT CGLNFSCFGY
DILLKWFLED SEITSITSSV TSITSSVTSS IKNVYTESKL TFQPKWTDHG KSVKCQVQHS
SKVLSERTVR LDVKYTPKLE IKVNPTEVEK NNSVTMTCRV NSSNPKLRTV AVSWFKDGRP
LEDQELEQEQ QMSKLILHSV TKDMRGKYRC QASNDIGPGE SEEVELTVHY APEPSRVHIY
PSPAEEGQSV ELICESLASP SATNYTWYHN RKPIPGDTQE KLRIPKVSPW HAGNYSCLAE
NRLGHGKIDQ EAKLDVHYAP KAVTTVIQSF TPILEGDSVT LVCRYNSSNP DVTSYRWNPQ
GSGSVLKPGV LRIQKVTWDS MPVSCAACNH KCSWALPVIL NVHYAPRDVK VLKVSPASEI
RAGQRVLLQC DFAESNPAEV RFFWKKNGSL VQEGRYLSFG SVSPEDSGNY NCMVNNSIGE
TLSQAWNLQV LYAPRRLRVS ISPGDHVMEG KKATLSCESD ANPPISQYTW FDSSGQDLHS
SGQKLRLEPL EVQHTGSYRC KGTNGIGTGE SPPSTLTVYY SPETIGKRVA LGLGFCLTIC
ILAIWGMKIQ KKWKQNRSQQ GLQENSSGQS FFVRNKKARR TPLSEGPQSQ GCYNPAMDDT
VSYAILRFPE SDTHNTGDAG TPATRAPPPN NSDSVTYSVI QKRPMGDYEN VNPSCPEDES
IHYSELVQFG AGKRPQAKED VDYVTLKH
Records:
Category Evidence Reference
A Inference Law CL, Sidorenko SP, Chandran KA, Zhao Z, Shen SH, Fischer EH, Clark EA., CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation, [8627166]
End of Record Details