ul_5076----
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PPBD protein
Gene name PLCG1
Synonyms EC 3.1.4.11; PLC-148; PLC-II; PLC-gamma-1; Phosphoinositide phospholipase C; Phospholipase C-gamma-1
GO annotations GO_component:
GO_function:calcium ion binding; hydrolase activity; phosphoinositide phospholipase C activity [PMID 2167438]; protein binding [PMID 10873601] [PMID 14722116]; receptor signaling protein activity [PMID 7681365]; signal transducer activity
GO_process: intracellular signaling cascade; lipid catabolism; lipid metabolism
RefSeq accession NP_002651
SwissProt accession P19174
Substrate protein
Gene name Bdkrb2( Description: bradykinin receptor, beta 2. )
Synonyms B2BKR; B2BRA
GO annotations GO_component: integral to membrane; integral to plasma membrane; membrane; plasma membrane
GO_function:bradykinin receptor activity; phosphoinositide phospholipase C activity; purinergic nucleotide receptor activity, G-protein coupled; receptor activity
GO_process: circulation; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; inflammatory response; sensory perception; sensory perception of pain; signal transduction; smooth muscle contraction; transmembrane receptor protein tyrosine kinase signaling pathway
RefSeq accession NP_775123
SwissProt accession
Sequence:(RefSeq accession:NP_775123; substrate region highlighted if known)
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MFNITTQALG SAHNGTFSEV NCPDTEWWSW LNAIQAPFLW VLFLLAALEN IFVLSVFCLH
KTNCTVAEIY LGNLAAADLI LACGLPFWAI TIANNFDWLF GEVLCRVVNT MIYMNLYSSI
CFLMLVSIDR YLALVKTMSM GRMRGVRWAK LYSLVIWSCT LLLSSPMLVF RTMKDYREEG
HNVTACVIVY PSRSWEVFTN MLLNLVGFLL PLSIITFCTV RIMQVLRNNE MKKFKEVQTE
KKATVLVLAV LGLFVLCWFP FQISTFLDTL LRLGVLSGCW NERAVDIVTQ ISSYVAYSNS
CLNPLVYVIV GKRFRKKSRE VYQAICRKGG CMGESVQMEN SMGTLRTSIS VDRQIHKLQD
WAGNKQ
Records:
Category Evidence Reference
A Mutagenesis Duchene J, Chauhan SD, Lopez F, Pecher C, Esteve JP, Girolami JP, Bascands JL, Schanstra JP., Direct protein-protein interaction between PLCgamma1 and the bradykinin B2 receptor--importance of growth conditions, [15607753]
End of Record Details