ul_5234----
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PPBD protein
Gene name PTPN11( Description: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1). )
Synonyms BPTP3; CFC; EC 3.1.3.48; MGC14433; NS1; PTP-1D; PTP-2C; PTP2C; Protein-tyrosine phosphatase 2C; SH-PTP2; SH-PTP3; SHP-2; SHP2; Shp2
GO annotations GO_component:
GO_function:hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity [PMID 7681589]; protein binding [PMID 9658397] [PMID 10209036]
GO_process: intracellular signaling cascade; protein amino acid dephosphorylation; sensory perception of sound
RefSeq accession NP_002825
SwissProt accession Q06124
Substrate protein
Gene name Klra1( Description: killer cell lectin-like receptor, subfamily A, member 1. )
Synonyms A1; Klra22; Ly49a; Ly49o<129>; Ly49v
GO annotations GO_component: external side of plasma membrane; integral to membrane; membrane; plasma membrane
GO_function:protein binding; receptor activity; signal transducer activity; sugar binding
GO_process: cell adhesion; defense response
RefSeq accession NP_057868
SwissProt accession
Sequence:(RefSeq accession:NP_057868; substrate region highlighted if known)
1
61
121
181
241
MSEQEVTYSM VRFHKSAGLQ KQVRPEETKG PREAGYRRCS FHWKFIVIAL GIFCFLLLVA
VSVLAIKIFQ YDQQKKLQEF LNHHNNCSNM QSDINLKDEM LKNKSIECDL LESLNRDQNR
LYNKTKTVLD SLQHTGRGDK VYWFCYGMKC YYFVMDRKTW SGCKQTCQSS SLSLLKIDDE
DELKFLQLVV PSDSCWVGLS YDNKKKDWAW IDNRPSKLAL NTRKYNIRDG GCMLLSKTRL
DNGNCDQVFI CICGKRLDKF PH
Records:
Category Evidence Reference
A Peptide library Olcese L, Lang P, Vely F, Cambiaggi A, Marguet D, Blery M, Hippen KL, Biassoni R, Moretta A, Moretta L, Cambier JC, Vivier E., Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases, [8648092]
End of Record Details