ul_5345----<table width="100%" border="0" cellpadding="5" cellspacing="1" bgcolor="#666666" >
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          <td width="91%" align="left"><strong>Record details:</strong> </td>
          <td width="9%" align="right"><a href="javascript:hide('ul_5345')" class="small">Hide</a></td>
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    <td colspan="2"><strong>PPBD protein </strong></td>
    
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        <td width="25%">Gene name </td>
        <td><a href="ppbd.php?s=PTPN11" title="PPBD proteins are named by using their Entrez Gene Name.">PTPN11</a>( Description: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1). )</td>
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        <td>Synonyms </td>
        <td>BPTP3; CFC; EC 3.1.3.48; MGC14433; NS1; PTP-1D; PTP-2C; PTP2C; Protein-tyrosine phosphatase 2C; SH-PTP2; SH-PTP3; SHP-2; SHP2; Shp2</td>
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        <td>GO annotations </td>
        <td>GO_component: <br>GO_function:<a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016787>hydrolase activity</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0004726>non-membrane spanning</a>
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0004726>protein tyrosine phosphatase activity</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=7681589>7681589</a>];
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005515>protein binding</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=9658397>9658397</a>] [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=10209036>10209036</a>]<br>GO_process: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007242>intracellular signaling cascade</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0006470>protein</a>
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0006470>amino acid dephosphorylation</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007605>sensory perception of sound</a></td>
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        <td>RefSeq accession </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_002825" target="_blank" >NP_002825</a></td>
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        <td>SwissProt accession </td>
        <td><a href="http://www.expasy.org/uniprot/Q06124" target="_blank" >Q06124</a></td>
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    <td  colspan="2"><strong>Substrate protein </strong></td>
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        <td width="25%">Gene name </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=full_report&list_uids=26365" target="_blank"  title="Substrate proteins are named by using their Entrez Gene Name.">Ceacam1</a>( Description: CEA-related cell adhesion molecule 1. )</td>
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        <td>Synonyms </td>
        <td>Bgp; Bgp1; C-CAM; CD66a; Cea-1; Cea-7; Cea1; Cea7; Hv-2; Hv2; MHVR; Mhv-1; bb-1; mCEA1; mmCGM1; mmCGM1a; mmCGM2</td>
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        <td>GO annotations </td>
        <td>GO_component: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016021>integral to membrane</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016020>membrane</a><br>GO_function:<a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0004872>receptor activity</a><br>GO_process: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0043406>positive regulation of MAPK activity</a></td>
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        <td>RefSeq accession </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001034274" target="_blank" >NP_001034274</a></td>
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        <td>SwissProt accession </td>
        <td><a href="http://www.expasy.org/uniprot/" target="_blank" ></a></td>
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    <td colspan="2" bgcolor="#CCCCCC"><strong>Sequence:</strong>(RefSeq accession:<a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001034274" target="_blank" >NP_001034274</a>; substrate region highlighted 
if known)</td></tr><tr bgcolor="#FFFFFF"><td colspan="2"><table align="center"><tr><td class="sequence" align="right">1<br>61<br>121<br>181<br>241<br>301<br>361<br>421<br>481<br></td><td><span class="sequence">MELASAHLHK GQVPWGGLLL TASLLASWSP ATTAEVTIEA VPPQVAEDNN VLLLVHNLPL <br>ALGAFAWYKG NTTAIDKEIA RFVPNSNMNF TGQAYSGREI IYSNGSLLFQ MITMKDMGVY <br>TLDMTDENYR RTQATVRFHV HPILLKPNIT SNNSNPVEGD DSVSLTCDSY TDPDNINYLW <br>SRNGESLSEG DRLKLSEGNR TLTLLNVTRN DTGPYVCETR NPVSVNRSDP FSLNIIYGPD <br>TPIISPSDIY LHPGSNLNLS CHAASNPPAQ YFWLINEKPH ASSQELFIPN ITTNNSGTYT <br>CFVNNSVTGL SRTTVKNITV LEPVTQPFLQ VTNTTVKELD SVTLTCLSND IGANIQWLFN <br>SQSLQLTERM TLSQNNSILR IDPIKREDAG EYQCEISNPV SVRRSNSIKL DIIFDPTQGG <br>LSDGAIAGIV IGVVAGVALI AGLAYFLYSR KSGGGSDQRD LTEHKPSASN HNLAPSDNSP <br>NKVDDVAYTV LNFNSQQPNR PTSAPS<font color='red'>SPRA TETVYSEVKK K</font></span></td></tr></table></td></tr><tr>
    <td colspan="2" bgcolor="#CCCCCC"><strong>Records:</strong></td>
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                <td align="center"><b>Category</b></td>
                <td align="center"><b>Evidence</b></td>
                <td align="center"><b>Reference</b></td>
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                <td  align="center">A</td>
                <td  align="center">Mutagenesis</td>
                <td  align="left"><a>Huber M, Izzi L, Grondin P, Houde C, Kunath T, Veillette A, Beauchemin N., The carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cells, [<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9867848" target="_blank" >9867848</a>] </a></td>
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    <td colspan="2" bgcolor="#999999" align="right"><strong>End of Record Details</strong></td>
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