ul_537----
Record details: Hide
PPBD protein
Gene name YWHAG( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide. )
Synonyms 14-3-3GAMMA; KCIP-1; Protein kinase C inhibitor protein 1
GO annotations GO_component: cytoplasm
GO_function:actin binding; insulin-like growth factor receptor binding [PMID 12482592]; protein domain specific binding; protein homodimerization activity; protein kinase C binding [PMID 10433554]; protein kinase C inhibitor activity [PMID 10433554]
GO_process: cytoskeleton organization and biogenesis; negative regulation of apoptosis; negative regulation of protein kinase activity [PMID 10433554]; regulation of mitosis; regulation of neuron differentiation [PMID 11824616]; regulation of signal transduction [PMID 10433554] [PMID 10486217]; regulation of synaptic plasticity [PMID 11824616]
RefSeq accession NP_036611
SwissProt accession P61981
Substrate protein
Gene name CENPJ( Description: centromere protein J. )
Synonyms BM032; CENP-J; CPAP; Centrosomal P4.1-associated protein; LAG-3-associated protein; LAP; LIP1; LYST-interacting protein 1; MCPH6; MGC131581; MGC131582; MGC142222; MGC142224
GO annotations GO_component: cytoskeleton; gamma-tubulin small complex [PMID 11003675]; microtubule
GO_function:protein binding [PMID 11003675]; tubulin binding [PMID 15047868]
GO_process: cell division [PMID 11003675]; microtubule nucleation [PMID 11003675]; microtubule polymerization [PMID 15047868]
RefSeq accession NP_060921
SwissProt accession Q9HC77
GO Pathway:
GO:0051301     cell division
Sequence:(RefSeq accession:NP_060921; substrate region highlighted if known)
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
MFLMPTSSEL NSGQNFLTQW MTNPSRAGVI LNRGFPILEA DKEKRAAVDI STSFPIKGTH
FSDSFSFINE EDSLLEEQKL ESNNPYKPQS DKSETHTAFP CIKKGPQVAA CHSAPGHQEE
NKNDFIPDRA SEFKEGAYKD PLFKKLEQLK EVQQKKQEQL KRQQLEQLQR LMEEQEKLLT
MVSGQCTLPG LSLLPDDQSQ KHRSPGNTTT GERATCCFPS YVYPDPTQEE TYPSNILSHE
QSNFCRTAHG DFVLTSKRAS PNLFSEAQYQ EAPVEKNNLK EENRNHPTGE SILCWEKVTE
QIQEANDKNL QKHDDSSEVA NIEERPIKAA IGERKQTFED YLEEQIQLEE QELKQKQLKE
AEGPLPIKAK PKQPFLKRGE GLARFTNAKS KFQKGKESKL VTNQSTSEDQ PLFKMDRQQL
QRKTALKNKE LCADNPILKK DSKARTKSGS VTLSQKPKML KCSNRKSLSP SGLKIQTGKK
CDGQFRDQIK FENKVTSNNK ENVTECPKPC DTGCTGWNKT QGKDRLPLST GPASRLAAKS
PIRETMKESE SSLDVSLQKK LETWEREKEK ENLELDEFLF LEQAADEISF SSNSSFVLKI
LERDQQICKG HRMSSTPVKA VPQKTNPADP ISHCNRSEDL DHTAREKESE CEVAPKQLHS
LSSADELREQ PCKIRKAVQK STSENQTEWN ARDDEGVPNS DSSTDSEEQL DVTIKPSTED
RERGISSRED SPQVCDDKGP FKDTRTQEDK RRDVDLDLSD KDYSSDESIM ESIKHKVSEP
SRSSSLSLSK MDFDDERTWT DLEENLCNHD VVLGNESTYG TPQTCYPNNE IGILDKTIKR
KIAPVKRGED LSKSRRSRSP PTSELMMKFF PSLKPKPKSD SHLGNELKLN ISQDQPPGDN
ARSQVLREKI IELETEIEKF KAENASLAKL RIERESALEK LRKEIADFEQ QKAKELARIE
EFKKEEMRKL QKERKVFEKY TTAARTFPDK KEREEIQTLK QQIADLREDL KRKETKWSST
HSRLRSQIQM LVRENTDLRE EIKVMERFRL DAWKRAEAIE SSLEVEKKDK LANTSVRFQN
SQISSGTQVE KYKKNYLPMQ GNPPRRSKSA PPRDLGNLDK GQAASPREPL EPLNFPDPEY
KEEEEDQDIQ GEISHPDGKV EKVYKNGCRV ILFPNGTRKE VSADGKTITV TFFNGDVKQV
MPDQRVIYYY AAAQTTHTTY PEGLEVLHFS SGQIEKHYPD GRKEITFPDQ TVKNLFPDGQ
EESIFPDGTI VRVQRDGNKL IEFNNGQREL HTAQFKRREY PDGTVKTVYA NGHQETKYRS
GRIRVKDKEG NVSMDTEL
Records:
Category Evidence Reference
A Inference Chen CY, Olayioye MA, Lindeman GJ, Tang TK., CPAP interacts with 14-3-3 in a cell cycle-dependent manner., [16516142]
End of Record Details