ul_5437----
Record details: Hide
PPBD protein
Gene name PTPN11( Description: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1). )
Synonyms BPTP3; CFC; EC 3.1.3.48; MGC14433; NS1; PTP-1D; PTP-2C; PTP2C; Protein-tyrosine phosphatase 2C; SH-PTP2; SH-PTP3; SHP-2; SHP2; Shp2
GO annotations GO_component:
GO_function:hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity [PMID 7681589]; protein binding [PMID 9658397] [PMID 10209036]
GO_process: intracellular signaling cascade; protein amino acid dephosphorylation; sensory perception of sound
RefSeq accession NP_002825
SwissProt accession Q06124
Substrate protein
Gene name BANK1( Description: B-cell scaffold protein with ankyrin repeats 1. )
Synonyms BANK; FLJ20706; FLJ34204
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_060405
SwissProt accession Q8NDB2
Sequence:(RefSeq accession:NP_060405; substrate region highlighted if known)
1
61
121
181
241
301
361
421
481
541
601
661
721
781
MLPAAPGKGL GSPDPAPCGP APPGNTKDII MIYEEDAEEW ALYLTEVFLH VVKREAILLY
RLENFSFRHL ELLNLTSYKC KLLILSNSLL RDLTPKKCQF LEKILHSPKS VVTLLCGVKS
SDQLYELLNI SQSRWEISTE QEPEDYISVI QSIIFKDSED YFEVNIPTDL RAKHSGEISE
RKEIEELSEA SRNTIPLAVV LPTEIPCENP GEIFIILRDE VIGDTVEVEF TSSNKRIRTR
PALWNKKVWC MKALEFPAGS VHVNVYCDGI VKATTKIKYY PTAKAKECLF RMADSGESLC
QNSIEELDGV LTSIFKHEIP YYEFQSLQTE ICSQNKYTHF KELPTLLHCA AKFGLKNLAI
HLLQCSGATW ASKMKNMEGS DPAHIAERHG HKELKKIFED FSIQEIDINN EQENDYEEDI
ASFSTYIPST QNPAFHHESR KTYGQSADGA EANEMEGEGK QNGSGMETKH SPLEVGSESS
EDQYDDLYVF IPGADPENNS QEPLMSSRPP LPPPRPVANA FQLERPHFTL PGTMVEGQME
RSQNWGHPGV RQETGDEPKG EKEKKEEEKE QEEEEDPYTF AEIDDSEYDM ILANLSIKKK
TGSRSFIINR PPAPTPRPTS IPPKEETTPY IAQVFQQKTA RRQSDDDKFR GLPKKQDRAR
IESPAFSTLR GCLTDGQEEL ILLQEKVKNG KMSMDEALEK FKHWQMGKSG LEMIQQEKLR
QLRDCIIGKR PEEENVYNKL TIVHHPGGKE TAHNENKFYN VHFSNKLPAR PQVEKEFGFC
CKKDH
Records:
Category Evidence Reference
A Inference Yokoyama K, Su Ih IH, Tezuka T, Yasuda T, Mikoshiba K, Tarakhovsky A, Yamamoto T., BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor, [11782428]
End of Record Details