ul_5471----
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PPBD protein
Gene name PTPN11( Description: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1). )
Synonyms BPTP3; CFC; EC 3.1.3.48; MGC14433; NS1; PTP-1D; PTP-2C; PTP2C; Protein-tyrosine phosphatase 2C; SH-PTP2; SH-PTP3; SHP-2; SHP2; Shp2
GO annotations GO_component:
GO_function:hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity [PMID 7681589]; protein binding [PMID 9658397] [PMID 10209036]
GO_process: intracellular signaling cascade; protein amino acid dephosphorylation; sensory perception of sound
RefSeq accession NP_002825
SwissProt accession Q06124
Substrate protein
Gene name HP0547( Description: cag pathogenicity island protein (cag26). )
Synonyms
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_207343
SwissProt accession
GO Pathway:
5120     KEGG pathway: Epithelial cell signaling in Helicobacter pylori infection
Sequence:(RefSeq accession:NP_207343; substrate region highlighted if known)
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MTNETIDQTR TPDQTQSQTA FDPQQFINNL QVAFIKVDNV VASFDPDQKP IVDKNDRDNR
QAFDGISQLR EEYSNKAIKN PTKKNQYFSD FIDKSNDLIN KDNLIDVESS TKSFQKFGDQ
RYQIFTSWVS HQKDPSKINT RSIRNFMENI IQPPIPDDKE KAEFLKSAKQ SFAGIIIGNQ
IRTDQKFMGV FDESLKERQE AEKNGGPTGG DWLDIFLSFI FNKKQSSDVK EAINQEPVPH
VQPDIATTTT DIQGLPPEAR DLLDERGNFS KFTLGDMEML DVEGVADIDP NYKFNQLLIH
NNALSSVLMG SHNGIEPEKV SLLYAGNGGF GDKHDWNATV GYKDQQGNNV ATLINVHMKN
GSGLVIAGGE KGINNPSFYL YKEDQLTGSQ RALSQEEIRN KVDFMEFLAQ NNTKLDNLSE
KEKEKFQNEI EDFQKDSKAY LDALGNDRIA FVSKKDTKHS ALITEFNNGD LSYTLKDYGK
KADKALDREK NVTLQGSLKH DGVMFVDYSN FKYTNASKNP NKGVGATNGV SHLEAGFNKV
AVFNLPDLNN LAITSFVRRN LENKLTAKGL SLQEANKLIK DFLSSNKELA GKALNFNKAV
AEAKSTGNYD EVKKAQKDLE KSLRKREHLE KEVEKKLESK SGNKNKMEAK AQANSQKDEI
FALINKEANR DARAIAYTQN LKGIKRELSD KLEKISKDLK DFSKSFDEFK NGKNKDFSKA
EETLKALKGS VKDLGINPEW ISKVENLNAA LNEFKNGKNK DFSKVTQAKS DLENSVKDVI
INQKVTDKVD NLNQAVSVAK AMGDFSRVEQ VLADLKNFSK EQLAQQAQKN EDFNTGKNSE
LYQSVKNSVN KTLVGNGLSG IEATALAKNF SDIKKELNEK FKNFNNNNNG LKNSTEPIYA
KVNKKKT
GQV ASPEEPIYTQ VAKKVNAKID RLNQIASGLG GVGQAAGFPL KRHDKVDDLS
KVGLSASPEP IYATIDDLGG PFPLKRHDKV DDLSKVGRSR NQELAQKIDN LNQAVSEAKA
GFFGNLEQTI DKLKDSTKKN VMNLYVESAK KVPASLSAKL DNYAINSHTR INSNIQNGAI
NEKATGMLTQ KNPEWLKLVN DKIVAHNVGS VSLSEYDKIG FNQKNMKDYS DSFKFSTKLN
NAVKDIKSGF THFLANAFST GYYCLARENA EHGIKNVNTK GGFQKS
Records:
Category Evidence Reference
A Inference Hatakeyama M., Helicobacter pylori CagA--a potential bacterial oncoprotein that functionally mimics the mammalian Gab family of adaptor proteins, [12650772]
End of Record Details