ul_5473----
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PPBD protein
Gene name PTPN11( Description: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1). )
Synonyms BPTP3; CFC; EC 3.1.3.48; MGC14433; NS1; PTP-1D; PTP-2C; PTP2C; Protein-tyrosine phosphatase 2C; SH-PTP2; SH-PTP3; SHP-2; SHP2; Shp2
GO annotations GO_component:
GO_function:hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity [PMID 7681589]; protein binding [PMID 9658397] [PMID 10209036]
GO_process: intracellular signaling cascade; protein amino acid dephosphorylation; sensory perception of sound
RefSeq accession NP_002825
SwissProt accession Q06124
Substrate protein
Gene name Sstr2( Description: somatostatin receptor 2. )
Synonyms SSTR-2; Smstr-2; Smstr2; sst2
GO annotations GO_component: membrane; membrane fraction; plasma membrane
GO_function:G-protein coupled receptor activity; receptor activity; rhodopsin-like receptor activity; signal transducer activity; somatostatin receptor activity
GO_process: G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; neuropeptide signaling pathway; signal transduction
RefSeq accession NP_033243
SwissProt accession
Sequence:(RefSeq accession:NP_033243; substrate region highlighted if known)
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MEMSSEQLNG SQVWVSSPFD LNGSLGPSNG SNQTEPYYDM TSNAVLTFIY FVVCVVGLCG
NTLVIYVILR YAKMKTITNI YILNLAIADE LFMLGLPFLA MQVALVHWPF GKAICRVVMT
VDGINQFTSI FCLTVMSIDR YLAVVHPIKS AKWRRPRTAK MINVAVWCVS LLVILPIMIY
AGLRSNQWGR SSCTINWPGE SGAWYTGFII YAFILGFLVP LTIICLCYLF IIIKVKSSGI
RVGSSKRKKS EKKVTRMVSI VVAVFIFCWL PFYIFNVSSV SVAISPTPAL KGMFDFVVIL
TYANSCANPI LYAFLSDNFK KSFQNVLCLV KADNSQSGAE DIIAWV
Records:
Category Evidence Reference
A Peptide library Lopez F, Pichereaux C, Burlet-Schiltz O, Pradayrol L, Monsarrat B, Esteve JP., Improved sensitivity of biomolecular interaction analysis mass spectrometry for the identification of interacting molecules, [12687608]
End of Record Details