ul_550----
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PPBD protein
Gene name YWHAG( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide. )
Synonyms 14-3-3GAMMA; KCIP-1; Protein kinase C inhibitor protein 1
GO annotations GO_component: cytoplasm
GO_function:actin binding; insulin-like growth factor receptor binding [PMID 12482592]; protein domain specific binding; protein homodimerization activity; protein kinase C binding [PMID 10433554]; protein kinase C inhibitor activity [PMID 10433554]
GO_process: cytoskeleton organization and biogenesis; negative regulation of apoptosis; negative regulation of protein kinase activity [PMID 10433554]; regulation of mitosis; regulation of neuron differentiation [PMID 11824616]; regulation of signal transduction [PMID 10433554] [PMID 10486217]; regulation of synaptic plasticity [PMID 11824616]
RefSeq accession NP_036611
SwissProt accession P61981
Substrate protein
Gene name HSPB6( Description: heat shock protein, alpha-crystallin-related, B6. )
Synonyms FLJ32389; Heat shock 20 kDa-like protein p20; Hsp20; HspB6
GO annotations GO_component:
GO_function:protein binding [PMID 16225851]; structural constituent of eye lens
GO_process: protein folding; response to unfolded protein
RefSeq accession NP_653218
SwissProt accession O14558
Sequence:(RefSeq accession:NP_653218; substrate region highlighted if known)
1
61
121
MEIPVPVQPS WLRRASAPLP GLSAPGRLFD QRFGEGLLEA ELAALCPTTL APYYLRAPSV
ALPVAQVPTD PGHFSVLLDV KHFSPEEIAV KVVGEHVEVH ARHEERPDEH GFVAREFHRR
YRLPPGVDPA AVTSALSPEG VLSIQAAPAS AQAPPPAAAK
Records:
Category Evidence Reference
A Mutagenesis Chernik IS, Seit-Nebi AS, Marston SB, Gusev NB., Small heat shock protein Hsp20 (HspB6) as a partner of 14-3-3gamma., [17109079]
End of Record Details