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          <td width="91%" align="left"><strong>Record details:</strong> </td>
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    <td colspan="2"><strong>PPBD protein </strong></td>
    
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        <td width="25%">Gene name </td>
        <td><a href="ppbd.php?s=PTPN11" title="PPBD proteins are named by using their Entrez Gene Name.">PTPN11</a>( Description: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1). )</td>
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        <td>Synonyms </td>
        <td>BPTP3; CFC; EC 3.1.3.48; MGC14433; NS1; PTP-1D; PTP-2C; PTP2C; Protein-tyrosine phosphatase 2C; SH-PTP2; SH-PTP3; SHP-2; SHP2; Shp2</td>
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        <td>GO annotations </td>
        <td>GO_component: <br>GO_function:<a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016787>hydrolase activity</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0004726>non-membrane spanning</a>
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0004726>protein tyrosine phosphatase activity</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=7681589>7681589</a>];
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005515>protein binding</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=9658397>9658397</a>] [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=10209036>10209036</a>]<br>GO_process: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007242>intracellular signaling cascade</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0006470>protein</a>
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0006470>amino acid dephosphorylation</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007605>sensory perception of sound</a></td>
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        <td>RefSeq accession </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_002825" target="_blank" >NP_002825</a></td>
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        <td>SwissProt accession </td>
        <td><a href="http://www.expasy.org/uniprot/Q06124" target="_blank" >Q06124</a></td>
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    <td  colspan="2"><strong>Substrate protein </strong></td>
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        <td width="25%">Gene name </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=full_report&list_uids=8778
" target="_blank"  title="Substrate proteins are named by using their Entrez Gene Name.">SIGLEC5</a>( Description: sialic acid binding Ig-like lectin 5. )</td>
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        <td>Synonyms </td>
        <td>CD170; CD170 antigen; CD33 antigen-like 2; CD33L2; OB-BP2; OB-binding protein 2; OBBP2; Obesity-binding protein 2; SIGLEC-5; Siglec-5</td>
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        <td>GO annotations </td>
        <td>GO_component: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016021>integral to membrane</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016020>membrane</a><br>GO_function:<a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005515>protein binding</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005529>sugar binding</a><br>GO_process: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007155>cell adhesion</a></td>
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        <td>RefSeq accession </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_003821" target="_blank" >NP_003821</a></td>
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        <td>SwissProt accession </td>
        <td><a href="http://www.expasy.org/uniprot/O15389" target="_blank" >O15389</a></td>
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    <td colspan="2" bgcolor="#CCCCCC"><strong>Sequence:</strong>(RefSeq accession:<a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_003821" target="_blank" >NP_003821</a>; substrate region highlighted 
if known)</td></tr><tr bgcolor="#FFFFFF"><td colspan="2"><table align="center"><tr><td class="sequence" align="right">1<br>61<br>121<br>181<br>241<br>301<br>361<br>421<br>481<br>541<br></td><td><span class="sequence">MLPLLLLPLL WGGSLQEKPV YELQVQKSVT VQEGLCVLVP CSFSYPWRSW YSSPPLYVYW <br>FRDGEIPYYA EVVATNNPDR RVKPETQGRF RLLGDVQKKN CSLSIGDARM EDTGSYFFRV <br>ERGRDVKYSY QQNKLNLEVT ALIEKPDIHF LEPLESGRPT RLSCSLPGSC EAGPPLTFSW <br>TGNALSPLDP ETTRSSELTL TPRPEDHGTN LTCQMKRQGA QVTTERTVQL NVSYAPQTIT <br>IFRNGIALEI LQNTSYLPVL EGQALRLLCD APSNPPAHLS WFQGSPALNA TPISNTGILE <br>LRRVRSAEEG GFTCRAQHPL GFLQIFLNLS VYSLPQLLGP SCSWEAEGLH CRCSFRARPA <br>PSLCWRLEEK PLEGNSSQGS FKVNSSSAGP WANSSLILHG GLSSDLKVSC KAWNIYGSQS <br>GSVLLLQGRS NLGTGVVPAA LGGAGVMALL CICLCLIFFL IVKARRKQAA GRPEKMDDED <br>PIMGTITSGS RKKPWPDSPG DQASPPGDAP P<font color='red'>LEEQKELHY ASLSFSEM</font>KS REPKDQEAPS <br>TTEYSEIKTS K</span></td></tr></table></td></tr><tr>
    <td colspan="2" bgcolor="#CCCCCC"><strong>Records:</strong></td>
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                <td align="center"><b>Category</b></td>
                <td align="center"><b>Evidence</b></td>
                <td align="center"><b>Reference</b></td>
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                <td  align="center">A</td>
                <td  align="center">Inference</td>
                <td  align="left"><a>Sweeney MC, Wavreille AS, Park J, Butchar JP, Tridandapani S, Pei D., Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains, [<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16274240" target="_blank" >16274240</a>] </a></td>
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    <td colspan="2" bgcolor="#999999" align="right"><strong>End of Record Details</strong></td>
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