ul_5598----
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PPBD protein
Gene name PTPN11( Description: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1). )
Synonyms BPTP3; CFC; EC 3.1.3.48; MGC14433; NS1; PTP-1D; PTP-2C; PTP2C; Protein-tyrosine phosphatase 2C; SH-PTP2; SH-PTP3; SHP-2; SHP2; Shp2
GO annotations GO_component:
GO_function:hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity [PMID 7681589]; protein binding [PMID 9658397] [PMID 10209036]
GO_process: intracellular signaling cascade; protein amino acid dephosphorylation; sensory perception of sound
RefSeq accession NP_002825
SwissProt accession Q06124
Substrate protein
Gene name GPR175( Description: G protein-coupled receptor 175. )
Synonyms FLJ32197; TPRA40
GO annotations GO_component: integral to membrane; membrane
GO_function:
GO_process:
RefSeq accession NP_057456
SwissProt accession Q86W33
Sequence:(RefSeq accession:NP_057456; substrate region highlighted if known)
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MDTLEEVTWA NGSTALPPPL APNISVPHRC LLLLYEDIGT SRVRYWDLLL LIPNVLFLIF
LLWKLPSARA KIRITSSPIF ITFYILVFVV ALVGIARAVV SMTVSTSNAA TVADKILWEI
TRFFLLAIEL SVIILGLAFG TWESKSSIKR VLAITTVLSL AYSVTQGTLE ILYPDAHLSA
EDFNIYGHGG RQFWLVSSCF FFLVYSLVVI LPKTPLKERI SLPSRRSFYV YAGILALLNL
LQGLGSVLLC FDIIEGLCCV DATTFLYFSF FAPLIYVAFL RGFFGSEPKI LFSYKCQVDE
TEEPDVHLPQ PYAVARREGL EAAGAAGASA ASYSSTQFDS AGGVAYLDDI ASMPCHTGSI
NSTDSERWKA INA
Records:
Category Evidence Reference
A Inference Sweeney MC, Wavreille AS, Park J, Butchar JP, Tridandapani S, Pei D., Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains, [16274240]
End of Record Details