ul_5695----
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PPBD protein
Gene name PTPN6
Synonyms EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; PTP-1C; Protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
GO annotations GO_component: cytoskeleton; membrane [PMID 10506221]
GO_function:hydrolase activity; protein binding [PMID 10660620]; protein tyrosine phosphatase activity [PMID 1732748]
GO_process: apoptosis [PMID 10506221]; G-protein coupled receptor protein signaling pathway [PMID 7781604]; intracellular signaling cascade; protein amino acid dephosphorylation [PMID 1732748]
RefSeq accession NP_002822
SwissProt accession P29350
Substrate protein
Gene name LILRB4( Description: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4. )
Synonyms CD85K; CD85k antigen; HM18; ILT-3; ILT3; Immunoglobulin-like transcript 3; LILRB5; LIR-5; LIR5; Leukocyte immunoglobulin-like receptor 5; Monocyte inhibitory receptor HM18
GO annotations GO_component: integral to membrane; plasma membrane [PMID 9548455]
GO_function:antigen binding [PMID 9151699]; receptor activity [PMID 9151699]
GO_process: immune response; signal transduction [PMID 9151699]
RefSeq accession NP_006838
SwissProt accession Q8NHJ6
GO Pathway:
GO:0003823     antigen binding
Sequence:(RefSeq accession:NP_006838; substrate region highlighted if known)
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MIPTFTALLC LGLSLGPRTD MQAGPLPKPT LWAEPGSVIS WGNSVTIWCQ GTLEAREYRL
DKEESPAPWD RQNPLEPKNK ARFSIPSMTE DYAGRYRCYY RSPVGWSQPS DPLELVMTGA
YSKPTLSALP SPLVTSGKSV TLLCQSRSPM DTFLLIKERA AHPLLHLRSE HGAQQHQAEF
PMSPVTSVHG GTYRCFSSHG FSHYLLSHPS DPLELIVSGS LEGPRPSPTR SVSTAAGPED
QPLMPTGSVP HSGLRRHWEV LIGVLVVSIL LLSLLLFLLL QHWRQGKHRT LAQRQADFQR
PPGAAEPEPK DGGLQRRSSP AADVQGENFC AAVKNTQPED GVEMDTRQSP HDEDPQAVTY
AKVKHSRPRR EMASPPSPLS GEFLDTKDRQ AEEDRQMDTE AAASEAPQDV TYARLHSFTL
RQKATEPPPS QEGASPAEPS VYATLAIH
Records:
Category Evidence Reference
A Inference Cella M, Dohring C, Samaridis J, Dessing M, Brockhaus M, Lanzavecchia A, Colonna M., A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing, [9151699]
End of Record Details