ul_5700----
Record details: Hide
PPBD protein
Gene name PTPN6
Synonyms EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; PTP-1C; Protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
GO annotations GO_component: cytoskeleton; membrane [PMID 10506221]
GO_function:hydrolase activity; protein binding [PMID 10660620]; protein tyrosine phosphatase activity [PMID 1732748]
GO_process: apoptosis [PMID 10506221]; G-protein coupled receptor protein signaling pathway [PMID 7781604]; intracellular signaling cascade; protein amino acid dephosphorylation [PMID 1732748]
RefSeq accession NP_002822
SwissProt accession P29350
Substrate protein
Gene name Klra7( Description: killer cell lectin-like receptor, subfamily A, member 7. )
Synonyms LGL-1; Ly-49G.1; Ly-49G.2; Ly-49G.3; Ly49G.4; Ly49g; Ly49g1; Ly49g2; MGC123448; MGC161317
GO annotations GO_component: integral to membrane; membrane; plasma membrane
GO_function:protein binding; receptor activity; sugar binding
GO_process: cell adhesion; defense response
RefSeq accession NP_055009
SwissProt accession
Sequence:(RefSeq accession:NP_055009; substrate region highlighted if known)
1
61
121
181
241
MSEQEVTYST VRFHESSRLQ KLVRTEEPQR PREACYRKYS VPWKLIVIAC GIFCFLLLVT
VALLAITIFQ HIQQKHELQE TLNCHDNCST TQSDVNLKDE LLRNKSIECR PGNDLLESLN
RDQKRWYSET KTFSDSSQHT GRGFEKYWFC YGIKCYYFDM DRKTWSGCKQ TCQISSLSLL
KIDNEDELKF LQNLAPSDIS WIGFSYDNKK KDWAWIDNGP SKLALNTTKY NIRDGLCMSL
SKTRLDNGDC GKSYICICGK RLDKFPY
Records:
Category Evidence Reference
A Inference Mason LH, Gosselin P, Anderson SK, Fogler WE, Ortaldo JR, McVicar DW., Differential tyrosine phosphorylation of inhibitory versus activating Ly-49 receptor proteins and their recruitment of SHP-1 phosphatase, [9379012]
End of Record Details