ul_5848----
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PPBD protein
Gene name PTPN6
Synonyms EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; PTP-1C; Protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
GO annotations GO_component: cytoskeleton; membrane [PMID 10506221]
GO_function:hydrolase activity; protein binding [PMID 10660620]; protein tyrosine phosphatase activity [PMID 1732748]
GO_process: apoptosis [PMID 10506221]; G-protein coupled receptor protein signaling pathway [PMID 7781604]; intracellular signaling cascade; protein amino acid dephosphorylation [PMID 1732748]
RefSeq accession NP_002822
SwissProt accession P29350
Substrate protein
Gene name HRASLS5( Description: HRAS-like suppressor family, member 5. )
Synonyms HRLP5
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_473449
SwissProt accession Q96KN8
Sequence:(RefSeq accession:NP_473449; substrate region highlighted if known)
1
61
121
181
241
MGLSPGAEGE YALRLPRIPP PLPKPASRTA GTGPKDQPPA LRRSAVPHSG LNSISPLELE
ESVGFAALVQ LPAKQPPPGT LEQGRSIQQG EKAVVSLETT PSQKADWSSI PKPENEGKLI
KQAAEGKPRP RPGDLIEIFR IGYEHWAIYV EDDCVVHLAP PSEEFEVGSI TSIFSNRAVV
KYSRLEDVLH
GCSWKVNNKL DGTYLPLPVD KIIQRTKKMV NKIVQYSLIE GNCEHFVNGL
RYGVPRSQQV EHALMEGAKA AGAVISAVVD SIKPKPITA
Records:
Category Evidence Reference
A Inference Sweeney MC, Wavreille AS, Park J, Butchar JP, Tridandapani S, Pei D., Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains, [16274240]
End of Record Details