ul_5852----
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PPBD protein
Gene name PTPN6
Synonyms EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; PTP-1C; Protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
GO annotations GO_component: cytoskeleton; membrane [PMID 10506221]
GO_function:hydrolase activity; protein binding [PMID 10660620]; protein tyrosine phosphatase activity [PMID 1732748]
GO_process: apoptosis [PMID 10506221]; G-protein coupled receptor protein signaling pathway [PMID 7781604]; intracellular signaling cascade; protein amino acid dephosphorylation [PMID 1732748]
RefSeq accession NP_002822
SwissProt accession P29350
Substrate protein
Gene name FCRL5( Description: Fc receptor-like 5. )
Synonyms BXMAS1; CD307; CD307 ant; DKFZp667E2019; DKFZp667F216; FCRH5; FLJ00333; FLJ00397; Fc receptor homolog 5; FcR-like protein 5; FcRH5; FcRL5; IRTA2; Immunoglobulin receptor translocation-associated gene 2 protein; MGC119590; MGC119592; MGC119593; PRO820; RP11-217A12.1
GO annotations GO_component: integral to membrane; membrane
GO_function:receptor activity
GO_process:
RefSeq accession NP_112571
SwissProt accession Q96RD9
Sequence:(RefSeq accession:NP_112571; substrate region highlighted if known)
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MLLWVILLVL APVSGQFART PRPIIFLQPP WTTVFQGERV TLTCKGFRFY SPQKTKWYHR
YLGKEILRET PDNILEVQES GEYRCQAQGS PLSSPVHLDF SSASLILQAP LSVFEGDSVV
LRCRAKAEVT LNNTIYKNDN VLAFLNKRTD FHIPHACLKD NGAYRCTGYK ESCCPVSSNT
VKIQVQEPFT RPVLRASSFQ PISGNPVTLT CETQLSLERS DVPLRFRFFR DDQTLGLGWS
LSPNFQITAM WSKDSGFYWC KAATMPHSVI SDSPRSWIQV QIPASHPVLT LSPEKALNFE
GTKVTLHCET QEDSLRTLYR FYHEGVPLRH KSVRCERGAS ISFSLTTENS GNYYCTADNG
LGAKPSKAVS LSVTVPVSHP VLNLSSPEDL IFEGAKVTLH CEAQRGSLPI LYQFHHEDAA
LERRSANSAG GVAISFSLTA EHSGNYYCTA DNGFGPQRSK AVSLSITVPV SHPVLTLSSA
EALTFEGATV TLHCEVQRGS PQILYQFYHE DMPLWSSSTP SVGRVSFSFS LTEGHSGNYY
CTADNGFGPQ RSEVVSLFVT VPVSRPILTL RVPRAQAVVG DLLELHCEAP RGSPPILYWF
YHEDVTLGSS SAPSGGEASF NLSLTAEHSG NYSCEANNGL VAQHSDTISL SVIVPVSRPI
LTFRAPRAQA VVGDLLELHC EALRGSSPIL YWFYHEDVTL GKISAPSGGG ASFNLSLTTE
HSGIYSCEAD NGPEAQRSEM VTLKVAVPVS RPVLTLRAPG THAAVGDLLE LHCEALRGSP
LILYRFFHED VTLGNRSSPS GGASLNLSLT AEHSGNYSCE ADNGLGAQRS ETVTLYITGL
TANRSGPFAT GVAGGLLSIA GLAAGALLLY CWLSRKAGRK PASDPARSPP DSDSQEPTYH
NVPAWEELQP VYTNANPRGE NVVYSEVRII QEKKKHAVAS DPRHLRNKGS PIIYSEVKVA
STPVSGSLFL ASSAPHR
Records:
Category Evidence Reference
A Inference Sweeney MC, Wavreille AS, Park J, Butchar JP, Tridandapani S, Pei D., Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains, [16274240]
End of Record Details