ul_5884----
Record details: Hide
PPBD protein
Gene name PTPN6
Synonyms EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; PTP-1C; Protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
GO annotations GO_component: cytoskeleton; membrane [PMID 10506221]
GO_function:hydrolase activity; protein binding [PMID 10660620]; protein tyrosine phosphatase activity [PMID 1732748]
GO_process: apoptosis [PMID 10506221]; G-protein coupled receptor protein signaling pathway [PMID 7781604]; intracellular signaling cascade; protein amino acid dephosphorylation [PMID 1732748]
RefSeq accession NP_002822
SwissProt accession P29350
Substrate protein
Gene name NPBWR1( Description: neuronal PAS domain protein 4. )
Synonyms Le-PAS; NXF; PASD10
GO annotations GO_component: integral to membrane [PMID 12401809]; membrane
GO_function:opioid receptor activity [PMID 7590751]; protein binding [PMID 12401809]; receptor activity; rhodopsin-like receptor activity
GO_process: G-protein coupled receptor protein signaling pathway [PMID 12401809]; neuropeptide signaling pathway; signal transduction; synaptic transmission [PMID 7590751]
RefSeq accession NP_005276
SwissProt accession P48145
Sequence:(RefSeq accession:NP_005276; substrate region highlighted if known)
1
61
121
181
241
301
MDNASFSEPW PANASGPDPA LSCSNASTLA PLPAPLAVAV PVVYAVICAV GLAGNSAVLY
VLLRAPRMKT VTNLFILNLA IADELFTLVL PINIADFLLR QWPFGELMCK LIVAIDQYNT
FSSLYFLTVM SADRYLVVLA TAESRRVAGR TYSAARAVSL AVWGIVTLVV LPFAVFARLD
DEQGRRQCVL VFPQPEAFWW RASRLYTLVL GFAIPVSTIC VLYTTLLCRL HAMRLDSHAK
ALERAKKRVT FLVVAILAVC LLCWTPYHLS TVVALTTDLP QTPLVIAISY FITSLSYANS
CLNPFLYAFL DASFRRNLRQ LITCRAAA
Records:
Category Evidence Reference
A Inference Sweeney MC, Wavreille AS, Park J, Butchar JP, Tridandapani S, Pei D., Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains, [16274240]
End of Record Details