ul_5900----
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PPBD protein
Gene name PTPN6
Synonyms EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; PTP-1C; Protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
GO annotations GO_component: cytoskeleton; membrane [PMID 10506221]
GO_function:hydrolase activity; protein binding [PMID 10660620]; protein tyrosine phosphatase activity [PMID 1732748]
GO_process: apoptosis [PMID 10506221]; G-protein coupled receptor protein signaling pathway [PMID 7781604]; intracellular signaling cascade; protein amino acid dephosphorylation [PMID 1732748]
RefSeq accession NP_002822
SwissProt accession P29350
Substrate protein
Gene name PRTFDC1
Synonyms CDNA FLJ11888 fis, clone HEMBA1007243, weakly similar to Chinese hamster hprt mRNA; Phosphoribosyl transferase domain containing 1; Phosphoribosyl transferase domain containing 1, isoform CRA_b
GO annotations GO_component: cytoplasm
GO_function:hypoxanthine phosphoribosyltransferase activity; transferase activity; transferase activity, transferring glycosyl groups
GO_process: nucleoside metabolism; purine ribonucleoside salvage
RefSeq accession NP_064585
SwissProt accession Q9NRG1
Sequence:(RefSeq accession:NP_064585; substrate region highlighted if known)
1
61
121
181
MAGSSEEAPD YGRGVVIMDD WPGYDLNLFT YPQHYYGDLE YVLIPHGIIV DRIERLAKDI
MKDIGYSDIM VLCVLKGGYK FCADLVEHLK NISRNSDRFV SMKVDFIRLK SYRNDQSMGE
MQIIGGDDLS TLAGKNVLIV EDVVGTGRTM KALLSNIEKY KPNMIKVASL LVKRTSRSDG
FRPDYAGFEI PNLFVVGYAL DYNEYFRDLN HICVINEHGK EKYRV
Records:
Category Evidence Reference
A Inference Sweeney MC, Wavreille AS, Park J, Butchar JP, Tridandapani S, Pei D., Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains, [16274240]
End of Record Details