ul_5904----
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PPBD protein
Gene name PTPN6
Synonyms EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; PTP-1C; Protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
GO annotations GO_component: cytoskeleton; membrane [PMID 10506221]
GO_function:hydrolase activity; protein binding [PMID 10660620]; protein tyrosine phosphatase activity [PMID 1732748]
GO_process: apoptosis [PMID 10506221]; G-protein coupled receptor protein signaling pathway [PMID 7781604]; intracellular signaling cascade; protein amino acid dephosphorylation [PMID 1732748]
RefSeq accession NP_002822
SwissProt accession P29350
Substrate protein
Gene name KIAA0319( Description: KIAA0319. )
Synonyms DLX2; DYLX2; DYX2
GO annotations GO_component: integral to membrane; membrane
GO_function:calcium ion binding
GO_process: homophilic cell adhesion
RefSeq accession NP_055624
SwissProt accession Q5VV43
Sequence:(RefSeq accession:NP_055624; substrate region highlighted if known)
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MAPPTGVLSS LLLLVTIAGC ARKQCSEGRT YSNAVISPNL ETTRIMRVSH TFPVVDCTAA
CCDLSSCDLA WWFEGRCYLV SCPHKENCEP KKMGPIRSYL TFVLRPVQRP AQLLDYGDMM
LNRGSPSGIW GDSPEDIRKD LPFLGKDWGL EEMSEYADDY RELEKDLLQP SGKQEPRGSA
EYTDWGLLPG SEGAFNSSVG DSPAVPAETQ QDPELHYLNE SASTPAPKLP ERSVLLPLPT
TPSSGEVLEK EKASQLQEQS SNSSGKEVLM PSHSLPPASL ELSSVTVEKS PVLTVTPGST
EHSIPTPPTS AAPSESTPSE LPISPTTAPR TVKELTVSAG DNLIITLPDN EVELKAFVAP
APPVETTYNY EWNLISHPTD YQGEIKQGHK QTLNLSQLSV GLYVFKVTVS SENAFGEGFV
NVTVKPARRV NLPPVAVVSP QLQELTLPLT SALIDGSQST DDTEIVSYHW EEINGPFIEE
KTSVDSPVLR LSNLDPGNYS FRLTVTDSDG ATNSTTAALI VNNAVDYPPV ANAGPNHTIT
LPQNSITLNG NQSSDDHQIV LYEWSLGPGS EGKHVVMQGV QTPYLHLSAM QEGDYTFQLK
VTDSSRQQST AVVTVIVQPE NNRPPVAVAG PDKELIFPVE SATLDGSSSS DDHGIVFYHW
EHVRGPSAVE MENIDKAIAT VTGLQVGTYH FRLTVKDQQG LSSTSTLTVA VKKENNSPPR
ARAGGRHVLV LPNNSITLDG SRSTDDQRIV SYLWIRDGQS PAAGDVIDGS DHSVALQLTN
LVEGVYTFHL RVTDSQGASD TDTATVEVQP DPRKSGLVEL TLQVGVGQLT EQRKDTLVRQ
LAVLLNVLDS DIKVQKIRAH SDLSTVIVFY VQSRPPFKVL KAAEVARNLH MRLSKEKADF
LLFKVLRVDT AGCLLKCSGH GHCDPLTKRC ICSHLWMENL IQRYIWDGES NCEWSIFYVT
VLAFTLIVLT GGFTWLCICC CKRQKRTKIR KKTKYTILDN MDEQERMELR PKYGIKHRST
EHNSSLMVSE SEFDSDQDTI FSREKMERGN PKVSMNGSIR NGASFSYCSK DR
Records:
Category Evidence Reference
A Inference Sweeney MC, Wavreille AS, Park J, Butchar JP, Tridandapani S, Pei D., Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains, [16274240]
End of Record Details