ul_5908----
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PPBD protein
Gene name PTPN6
Synonyms EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; PTP-1C; Protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
GO annotations GO_component: cytoskeleton; membrane [PMID 10506221]
GO_function:hydrolase activity; protein binding [PMID 10660620]; protein tyrosine phosphatase activity [PMID 1732748]
GO_process: apoptosis [PMID 10506221]; G-protein coupled receptor protein signaling pathway [PMID 7781604]; intracellular signaling cascade; protein amino acid dephosphorylation [PMID 1732748]
RefSeq accession NP_002822
SwissProt accession P29350
Substrate protein
Gene name RANBP17( Description: RAN binding protein 17. )
Synonyms FLJ32916
GO annotations GO_component: cytoplasm; nuclear pore [PMID 11024021]; nucleus
GO_function:binding; GTP binding [PMID 11024021]; protein transporter activity
GO_process: protein import into nucleus, docking; protein transport
RefSeq accession NP_075048
SwissProt accession Q9H2T7
Sequence:(RefSeq accession:NP_075048; substrate region highlighted if known)
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MALHFQSLAE LEVLCTHLYI GTDLTQRIEA EKALLELIDS PECLSKCQLL LEQGTTSYAQ
LLAATCLSKL VSRVSPLPVE QRMDIRNYIL NYVASQPKLA PFVIQALIQV IAKITKLGWF
EVQKDQFVFR EIIADVKKFL QGTVEHCIIG VIILSELTQE MNLVDYSRPS AKHRKIATSF
RDTSLKDVLV LACSLLKEVF AKPLNLQDQC QQNLVMQVLK LVLNCLNFDF IGSSADESAD
DLCTVQIPTT WRTIFLEPET LDLFFNLYHS LPPLLSQLAL SCLVQFASTR RSLFNSPERA
KYLGNLIKGV KRILENPQGL SDPGNYHEFC RFLARLKTNY QLGELVMVKE YPEVIRLIAN
FTITSLQHWE FAPNSVHYLL TLWQRMVASV PFVKSTEPHL LDTYAPEITK AFITSRLDSV
AIVVRDHLDD PLDDTATVFQ QLEQLCTVSR CEYEKTCALL VQLFDQNAQN YQKLLHPYSG
VTVDITIQEG RLAWLVYLVG TVVGGRLTYT STDEHDAMDG ELSCRVFQLI SLMDTGLPRC
CNEKIELAIL WFLDQFRKTY VGDQLQRTSK VYARMSEVLG ITDDNHVLET FMTKIVTNLK
YWGRYEPVIS RTLQFLNDLS VGYILLKKLV KIDAVKFMLK NHTSEHFPFL GISDNHSLSD
FRCRTTFYTA LTRLLMVDLG EDEDEFENFM LPLTVAFETV LQIFNNNFKQ EDVKRMLIGL
ARDLRGIAFA LNTKTSYTML FDWMYPTYLP LLQNAVERWY GEPTCTTPIL KLMAELMQNR
SQRLNFDVSS PNGILLFREA SKMVCTYGNQ ILSLGSLSKD QIYPMKLKGI SICYSALKSA
LCGNYVSFGV FKLYGDNHFD NVLQAFVKML LSVSHSDLLQ YRKLSQSYYP LLECLTQDHM
SFIINLEPPV LMYVLTSISE GLTTLDTVVS SSCCTSLDYI VTYLFKHIAK EGKKPLRCRE
ATQAGQRLLH FMQQNPDVLQ QMMSVLMNTI VFEDCRNQWS VSRPLLGLIL LNEKYFSELR
ASLINSQPLP KQEVLAQCFR NLMEGVEQNL SVKNRDRFTQ NLSVFRRDVA EALRSDGNTE
PCSLDMMS
Records:
Category Evidence Reference
A Inference Sweeney MC, Wavreille AS, Park J, Butchar JP, Tridandapani S, Pei D., Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains, [16274240]
End of Record Details