ul_5992----
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PPBD protein
Gene name PTPN6
Synonyms EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; PTP-1C; Protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
GO annotations GO_component: cytoskeleton; membrane [PMID 10506221]
GO_function:hydrolase activity; protein binding [PMID 10660620]; protein tyrosine phosphatase activity [PMID 1732748]
GO_process: apoptosis [PMID 10506221]; G-protein coupled receptor protein signaling pathway [PMID 7781604]; intracellular signaling cascade; protein amino acid dephosphorylation [PMID 1732748]
RefSeq accession NP_002822
SwissProt accession P29350
Substrate protein
Gene name CLEC4A
Synonyms C-type lectin DDB27; C-type lectin superfamily member 6; Dendritic cell immunoreceptor; Lectin-like immunoreceptor
GO annotations GO_component: integral to plasma membrane [PMID 10438934]; membrane
GO_function:sugar binding; transmembrane receptor activity [PMID 10438934]
GO_process: antimicrobial humoral response (sensu Vertebrata) [PMID 10438934]; cell adhesion [PMID 10438934]; cell surface receptor linked signal transduction [PMID 10438934]; immune response
RefSeq accession NP_057268
SwissProt accession Q9UMR7
Sequence:(RefSeq accession:NP_057268; substrate region highlighted if known)
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MTSEITYAEV RFKNEFKSSG INTASSAASK ERTAPHKSNT GFPKLLCASL LIFFLLLAIS
FFIAFVIFFQ KYSQLLEKKT TKELVHTTLE CVKKNMPVEE TAWSCCPKNW KSFSSNCYFI
STESASWQDS EKDCARMEAH LLVINTQEEQ DFIFQNLQEE SAYFVGLSDP EGQRHWQWVD
QTPYNESSTF WHPREPSDPN ERCVVLNFRK SPKRWGWNDV NCLGPQRSVC EMMKIHL
Records:
Category Evidence Reference
A Inference Sweeney MC, Wavreille AS, Park J, Butchar JP, Tridandapani S, Pei D., Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains, [16274240]
End of Record Details