ul_6143----
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PPBD protein
Gene name RASA1
Synonyms GAP; GTPase-activating protein; Ras p21 protein activator; RasGAP; p120GAP
GO annotations GO_component: cytoplasm [PMID 2821624]; intracellular
GO_function:GTPase binding [PMID 2122974]; potassium channel inhibitor activity [PMID 1553544]; Ras GTPase activator activity [PMID 2188736]; receptor binding [PMID 2157284] [PMID 2176151]
GO_process: actin cytoskeleton organization and biogenesis; cell adhesion; cytokinesis; embryonic development; intracellular signaling cascade [PMID 1581965]; negative regulation of cell adhesion [PMID 8344248]; negative regulation of cell-matrix adhesion [PMID 8344248]; negative regulation of neuron apoptosis; positive regulation of anti-apoptosis [PMID 15542850]; regulation of actin filament polymerization [PMID 8344248]; regulation of cell shape [PMID 9113414]; regulation of RNA metabolism [PMID 9113414]; regulation of small GTPase mediated signal transduction; vasculogenesis
RefSeq accession NP_002881
SwissProt accession P20936
Substrate protein
Gene name btl( Description: breathless. )
Synonyms 0844/01; BTL/FGFR2; Btl; CG32134; CG6714; CT20816; D-FGFR; DFGF-R1; DFR2; Dfr-2; DmHD-311; FGFR; FGFR1; Fgf-r; dFGFR; dev; dtk2
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_729956
SwissProt accession
Sequence:(RefSeq accession:NP_729956; substrate region highlighted if known)
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1021
MAKVPITLVM IIAIVSAAAD LGCDYGHHRC YIDVTVENSP RQRHLLSDMD ITLQCVRPMA
KWFYEDKFQL RATLLRLERA QSGNSGNYGC LDSQNRWYNI SLVVGHKEPV GNDIASFVKL
EDAPALPESD LFFQPLNESR SLKLLQPLPK TVQRTAGGLF QLNCSPMDPD AKGVNISWLH
NDTQILGGRG RIKLKRWSLT VGQLQPEDAG SYHCELCVEQ DCQRSNPTQL EVISRKHTVP
MLKPGYPRNT SIALGDNVSI ECLLEDSALE PKITWLHKGN ADNIDDLLQR LREQSQLPVD
VTRLITRMDE PQVLRLGNVL MEDGGWYICI AENQVGRTVA ASYVDLYSPS DTTTVRTTTT
TTVASPIPTA STGEDNDDDV ENPAAEASGG VGPPVFRKEL KRLQHSLSGN TVNLACPVYG
KANITWTKDK KPLNRELGVY VQKNWTLRFV EATSEDSGLY NCKVCNAWGC IQFDFSVQIN
DRTRSAPIIV VPQNQTVKVN GSLVMKCTVY SDLHPTVSWK RVVLKNASLD GLKSVEIQNL
NFTVTNDSVV LTLRNVTFDQ EGWYTCLASS GLGRSNSSVY LRVVSPLPPL EIYALLHAHP
LGFTLAAITI VALFLLGSAF ITFMLRRLRR EKLLKLRIET VHQWTKKVII YRPGGEEGSG
CSSGDLQMPV IRIEKQRTTV STTGTGGTDP AQGFNEYEFP LDSNWEIPRQ QLSLGSILGE
GAFGRVVMAE AEGLPRSPQL AETIVAVKMV KEEHTDTDMA SLVREMEVMK MIGKHINIIN
LLGCCSQGGP LWVIVEYAPH GNLKDFLKQN RPGAPQRRSD SDGYLDDKPL ISTQHLGEKE
LTKFAFQIAR GMEYLASRRC IHRDLAARNV LVSDGYVMKI ADFGLARDIQ DTEYYRKNTN
GRLPIKWMAP ESLQEKKYDS QSDVWSYGVL LWEIMTYGDQ PYPHILSAEE LYSYLITGQR
MEKPAKCSLN IYVVMRQCWH FESCARPTFA ELVESFDGIL QQASSNPNDA YLDLSMPMLE
TPPSSGDEDD GSDTETFRET SPLRYQYTYK FN
Records:
Category Evidence Reference
A Peptide library Woodcock SA, Hughes DA., p120 Ras GTPase-activating protein associates with fibroblast growth factor receptors in Drosophila, [15030317]
End of Record Details