ul_6144----
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PPBD protein
Gene name RASA1
Synonyms GAP; GTPase-activating protein; Ras p21 protein activator; RasGAP; p120GAP
GO annotations GO_component: cytoplasm [PMID 2821624]; intracellular
GO_function:GTPase binding [PMID 2122974]; potassium channel inhibitor activity [PMID 1553544]; Ras GTPase activator activity [PMID 2188736]; receptor binding [PMID 2157284] [PMID 2176151]
GO_process: actin cytoskeleton organization and biogenesis; cell adhesion; cytokinesis; embryonic development; intracellular signaling cascade [PMID 1581965]; negative regulation of cell adhesion [PMID 8344248]; negative regulation of cell-matrix adhesion [PMID 8344248]; negative regulation of neuron apoptosis; positive regulation of anti-apoptosis [PMID 15542850]; regulation of actin filament polymerization [PMID 8344248]; regulation of cell shape [PMID 9113414]; regulation of RNA metabolism [PMID 9113414]; regulation of small GTPase mediated signal transduction; vasculogenesis
RefSeq accession NP_002881
SwissProt accession P20936
Substrate protein
Gene name htl( Description: heartless. )
Synonyms CG7223; CT22273; CT39172; DFGF-R1; DFGF-R2; DFR-1; DFR1; DFR1/DFGF-R2; DPR3; DTRK(FR1); DmHD-38; EMS2; FGF-R2; FGFR; FGFR2; FR1; HTL/FGFR1; Htl; dtk1; i100; i150; i79; j372
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_732286
SwissProt accession
Sequence:(RefSeq accession:NP_732286; substrate region highlighted if known)
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721
MAAAWSWRAS HSTITMTSGS LVVLFLLLSI WQPAVQVEGR RQMANSQEMI KDHLGARSQN
KTPAITNNAN QSSTSSADLD DGAADDDDNK ADLPVNVSSK PYWRNPKKMS FLQTRPSGSL
LTLNCHALGN PEPNITWYRN GTVDWTRGYG SLKRNRWTLT MEDLVPGDCG NYTCKVCNSL
GCIRHDTQVI VSDRVNHKPI LMTGPLNLTL VVNSTGSMHC KYLSDLTSKK AWIFVPCHGM
TNCSNNRSII AEDKDQLDFV NVRMEQEGWY TCVESNSLGQ SNSTAYLRVV RSLHVLEAGV
ASGSLHSTSF VYIFVFGGLI FIFMTTLFVF YAIRKMKHEK VLKQRIETVH QWTKKVIIFK
PEGGGDSSGS MDTMIMPVVR IQKQRTTVLQ NGNEPAPFNE YEFPLDSNWE LPRSHLVLGA
TLGEGAFGRV VMAEVNNAIV AVKMVKEGHT DDDIASLVRE MEVMKIIGRH INIINLLGCC
SQNGPLYVIV EYAPHGNLKD FLYKNRPFGR DQDRDSSQPP PSPPAHVITE KDLIKFAHQI
ARGMDYLASR RCIHRDLAAR NVLVSDDYVL KIADFGLARD IQSTDYYRKN TNGRLPIKWM
APESLQEKFY DSKSDVWSYG ILLWEIMTYG QQPYPTIMSA EELYTYLMSG QRMEKPAKCS
MNIYILMRQC WHFNADDRPP FTEIVEYMDK LLQTKEDYLD VDIANLDTPP STSDEEEDET
DNLQKWCNY
Records:
Category Evidence Reference
A Peptide library Woodcock SA, Hughes DA., p120 Ras GTPase-activating protein associates with fibroblast growth factor receptors in Drosophila, [15030317]
End of Record Details