ul_6279----
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PPBD protein
Gene name SH3BP2( Description: SH3-domain binding protein 2. )
Synonyms 3BP2; CRBM; CRPM; FLJ42079; RES4-23
GO annotations GO_component:
GO_function:SH3/SH2 adaptor activity [PMID 9299232]
GO_process: intracellular signaling cascade
RefSeq accession NP_003014
SwissProt accession P78314
Substrate protein
Gene name Flt3( Description: FMS-like tyrosine kinase 3. )
Synonyms B230315G04; CD135; Flk-2; Flt-3; Ly72; MGC124377; MGC124378
GO annotations GO_component: membrane
GO_function:ATP binding; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein-tyrosine kinase activity; receptor activity; transferase activity; transmembrane receptor protein tyrosine kinase activity
GO_process: lymphocyte differentiation; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway
RefSeq accession NP_034359
SwissProt accession
Sequence:(RefSeq accession:NP_034359; substrate region highlighted if known)
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MRALAQRSDR RLLLLVVLSV MILETVTNQD LPVIKCVLIS HENNGSSAGK PSSYRMVRGS
PEDLQCAPRR QSEGTVYEAA TVEVAESGSI TLQVQLATPG DLSCLWVFKH SSLGCQPHFD
LQNRGIVSMA ILNVTETQAG EYLLHIQSEA ANYTVLFTVN VRDTQLYVLR RPYFRKMENQ
DALLCISEGV PEPTVEWVLC SSHRESCKEE GPAVVRKEEK VLHELFGTDI RCCARNALGR
ECTKLFTIDL NQAPQSTLPQ LFLKVGEPLW IRCKAIHVNH GFGLTWELED KALEEGSYFE
MSTYSTNRTM IRILLAFVSS VGRNDTGYYT CSSSKHPSQS ALVTILEKGF INATSSQEEY
EIDPYEKFCF SVRFKAYPRI RCTWIFSQAS FPCEQRGLED GYSISKFCDH KNKPGEYIFY
AENDDAQFTK MFTLNIRKKP QVLANASASQ ASCSSDGYPL PSWTWKKCSD KSPNCTEEIP
EGVWNKKANR KVFGQWVSSS TLNMSEAGKG LLVKCCAYNS MGTSCETIFL NSPGPFPFIQ
DNISFYATIG LCLPFIVVLI VLICHKYKKQ FRYESQLQMI QVTGPLDNEY FYVDFRDYEY
DLKWEFPREN LEFGKVLGSG AFGRVMNATA YGISKTGVSI QVAVKMLKEK ADSCEKEALM
SELKMMTHLG HHDNIVNLLG ACTLSGPVYL IFEYCCYGDL LNYLRSKREK FHRTWTEIFK
EHNFSFYPTF QAHSNSSMPG SREVQLHPPL DQLSGFNGNL IHSEDEIEYE NQKRLAEEEE
EDLNVLTFED LLCFAYQVAK GMEFLEFKSC VHRDLAARNV LVTHGKVVKI CDFGLARDIL
SDSSYVVRGN ARLPVKWMAP ESLFEGIYTI KSDVWSYGIL LWEIFSLGVN PYPGIPVDAN
FYKLIQSGFK MEQPFYATEG IYFVMQSCWA FDSRKRPSFP NLTSFLGCQL AEAEEAMYQN
MGGNVPEHPS IYQNRRPLSR EAGSEPPSPQ AQVKIHGERS
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details