ul_6285----
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PPBD protein
Gene name SH3BP2( Description: SH3-domain binding protein 2. )
Synonyms 3BP2; CRBM; CRPM; FLJ42079; RES4-23
GO annotations GO_component:
GO_function:SH3/SH2 adaptor activity [PMID 9299232]
GO_process: intracellular signaling cascade
RefSeq accession NP_003014
SwissProt accession P78314
Substrate protein
Gene name FCER1A( Description: Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide. )
Synonyms FCE1A; Fc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alpha
GO annotations GO_component: integral to plasma membrane [PMID 2964640]; plasma membrane [PMID 1535625]
GO_function:IgE binding; receptor activity; receptor signaling protein activity
GO_process: immune response
RefSeq accession NP_001992
SwissProt accession P12319
Sequence:(RefSeq accession:NP_001992; substrate region highlighted if known)
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61
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MAPAMESPTL LCVALLFFAP DGVLAVPQKP KVSLNPPWNR IFKGENVTLT CNGNNFFEVS
STKWFHNGSL SEETNSSLNI VNAKFEDSGE YKCQHQQVNE SEPVYLEVFS DWLLLQASAE
VVMEGQPLFL RCHGWRNWDV YKVIYYKDGE ALKYWYENHN ISITNATVED SGTYYCTGKV
WQLDYESEPL NITVIKAPRE KYWLQFFIPL LVVILFAVDT GLFISTQQQV TFLLKIKRTR
KGFRLLNPHP KPNPKNN
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details