ul_6289----
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PPBD protein
Gene name SH3BP2( Description: SH3-domain binding protein 2. )
Synonyms 3BP2; CRBM; CRPM; FLJ42079; RES4-23
GO annotations GO_component:
GO_function:SH3/SH2 adaptor activity [PMID 9299232]
GO_process: intracellular signaling cascade
RefSeq accession NP_003014
SwissProt accession P78314
Substrate protein
Gene name CSF3R
Synonyms CD114 antigen; G-CSF-R
GO annotations GO_component: integral to plasma membrane [PMID 7542747]; membrane
GO_function:hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; receptor activity [PMID 7542747]
GO_process: cell adhesion; defense response [PMID 7542747]; signal transduction [PMID 1371413]
RefSeq accession NP_000751
SwissProt accession Q99062
Sequence:(RefSeq accession:NP_000751; substrate region highlighted if known)
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MARLGNCSLT WAALIILLLP GSLEECGHIS VSAPIVHLGD PITASCIIKQ NCSHLDPEPQ
ILWRLGAELQ PGGRQQRLSD GTQESIITLP HLNHTQAFLS CCLNWGNSLQ ILDQVELRAG
YPPAIPHNLS CLMNLTTSSL ICQWEPGPET HLPTSFTLKS FKSRGNCQTQ GDSILDCVPK
DGQSHCCIPR KHLLLYQNMG IWVQAENALG TSMSPQLCLD PMDVVKLEPP MLRTMDPSPE
AAPPQAGCLQ LCWEPWQPGL HINQKCELRH KPQRGEASWA LVGPLPLEAL QYELCGLLPA
TAYTLQIRCI RWPLPGHWSD WSPSLELRTT ERAPTVRLDT WWRQRQLDPR TVQLFWKPVP
LEEDSGRIQG YVVSWRPSGQ AGAILPLCNT TELSCTFHLP SEAQEVALVA YNSAGTSRPT
PVVFSESRGP ALTRLHAMAR DPHSLWVGWE PPNPWPQGYV IEWGLGPPSA SNSNKTWRME
QNGRATGFLL KENIRPFQLY EIIVTPLYQD TMGPSQHVYA YSQEMAPSHA PELHLKHIGK
TWAQLEWVPE PPELGKSPLT HYTIFWTNAQ NQSFSAILNA SSRGFVLHGL EPASLYHIHL
MAASQAGATN STVLTLMTLT PEGSELHIIL GLFGLLLLLT CLCGTAWLCC SPNRKNPLWP
SVPDPAHSSL GSWVPTIMEE DAFQLPGLGT PPITKLTVLE EDEKKPVPWE SHNSSETCGL
PTLVQTYVLQ GDPRAVSTQP QSQSGTSDQV LYGQLLGSPT SPGPGHYLRC DSTQPLLAGL
TPSPKSYENL WFQAS
PLGTL VTPAPSQEDD CVFGPLLNFP LLQGIRVHGM EALGSF
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details