ul_63----
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PPBD protein
Gene name SFN( Description: stratifin. )
Synonyms Epithelial cell marker protein 1; Stratifin; YWHAS
GO annotations GO_component: cytoplasm [PMID 10767298]; extracellular space [PMID 8515476]
GO_function:protein domain specific binding; protein kinase C inhibitor activity [PMID 8515476]
GO_process: cell proliferation [PMID 10767298]; negative regulation of protein kinase activity [PMID 8515476]; regulation of progression through cell cycle [PMID 10767298]; signal transduction [PMID 8515476]
RefSeq accession NP_006133
SwissProt accession P31947
Substrate protein
Gene name Nr4a1( Description: nuclear receptor subfamily 4, group A, member 1. )
Synonyms GFRP1; Gfrp; Hbr-1; Hbr1; Hmr; N10; N10 nuclear protein; NGFI-B; NGFIB; NP10; Nuclear hormone receptor NUR/77; Orphan nuclear receptor HMR; TIS1; TR3; nur77
GO annotations GO_component: nucleus
GO_function:DNA binding; ligand-dependent nuclear receptor activity; metal ion binding; protein binding; receptor activity; sequence-specific DNA binding; steroid hormone receptor activity; transcription factor activity; transcription regulator activity; zinc ion binding
GO_process: induction of apoptosis; negative regulation of caspase activity; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription; regulation of transcription, DNA-dependent; transcription
RefSeq accession NP_034574
SwissProt accession P12813
Sequence:(RefSeq accession:NP_034574; substrate region highlighted if known)
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MPCIQAQYGT PATSPGPRDH LTGDPLALEF GKPTMDLASP ETAPAAPATL PSFSTFMDGY
TGEFDTFLYQ LPGTTQPCSS ACSSASSTSS SSSSATSPAS ASFKFEDFQV YGCYPGTLSG
PLDETLSSSG SEYYGSPCSA PSPSTPNFQP SQLSPWDGSF GHFSPSQTYE GLWAWTEQLP
KASSGPPPPP TFFSFSPPTG PSPSLAQSSL KLFPPPATHQ LGEGESYSMP AAFPGLAPTS
PNRDTSGILD APVTSTKSRS GASGGSEGRC AVCGDNASCQ HYGVRTCEGC KGFFKRTVQK
SAKYICLANK DCPVDKRRRN RCQFCRFQKC LAVGMVKEVV RTDSLKGRRG RLPSKPKQPP
DASPTNLLTS LIRAHLDSGP STAKLDYSKF QELVLPRFGK EDAGDVQQFY DLLSGSLDVI
RKWAEKIPGF IELCPGDQDL LLESAFLELF ILRLAYRSKP GEGKLIFCSG LVLHQLQCAR
GFGDWIDNIL AFSRSLHSLG VDVPAFACLS ALVLITDRHG LQDPRRVEEL QNRIASCLKE
HMATVAGDPQ PASCLSRLLG KLPELRTLCT QGLQRIFCLK LEDLVPPPPI VDKIFMDTLS
F
Records:
Category Evidence Reference
A Inference Wingate AD, Campbell DG, Peggie M, Arthur JS., Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation., [16223362]
End of Record Details