ul_670----
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PPBD protein
Gene name YWHAQ( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide. )
Synonyms 14-3-3; 14-3-3 protein T-cell; 14-3-3 protein tau; 1C5; HS1; HS1 protein
GO annotations GO_component:
GO_function:protein domain specific binding; protein kinase C inhibitor activity
GO_process: exocytosis; regulation of progression through cell cycle
RefSeq accession NP_006817
SwissProt accession P27348
Substrate protein
Gene name NFATC4( Description: nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3. )
Synonyms NF-AT3; NF-ATc4; NFAT4; NFATX; NFATc4; T-cell transcription factor NFAT3
GO annotations GO_component: nucleus
GO_function:transcription coactivator activity [PMID 7749981]; transcription factor activity
GO_process: inflammatory response [PMID 7749981]; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter [PMID 7749981]
RefSeq accession NP_004545
SwissProt accession Q14934
Sequence:(RefSeq accession:NP_004545; substrate region highlighted if known)
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241
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361
421
481
541
601
661
721
781
841
901
MGAASCEDEE LEFKLVFGEE KEAPPLGAGG LGEELDSEDA PPCCRLALGE PPPYGAAPIG
IPRPPPPRPG MHSPPPRPAP SPGTWESQPA RSVRLGGPGG GAGGAGGGRV LECPSIRITS
ISPTPEPPAA LEDNPDAWGD GSPRDYPPPE GFGGYREAGG QGGGAFFSPS PGSSSLSSWS
FFSDASDEAA LYAACDEVES ELNEAASRFG LGSPLPSPRA SPRPWTPEDP WSLYGPSPGG
RGPEDSWLLL SAPGPTPASP RPASPCGKRR YSSSGTPSSA SPALSRRGSL GEEGSEPPPP
PPLPLARDPG SPGPFDYVGA PPAESIPQKT RRTSSEQAVA LPRSEEPASC NGKLPLGAEE
SVAPPGGSRK EVAGMDYLAV PSPLAWSKAR IGGHSPIFRT SALPPLDWPL PSQYEQLELR
IEVQPRAHHR AHYETEGSRG AVKAAPGGHP VVKLLGYSEK PLTLQMFIGT ADERNLRPHA
FYQVHRITGK MVATASYEAV VSGTKVLEMT LLPENNMAAN IDCAGILKLR NSDIELRKGE
TDIGRKNTRV RLVFRVHVPQ GGGKVVSVQA ASVPIECSQR SAQELPQVEA YSPSACSVRG
GEELVLTGSN FLPDSKVVFI ERGPDGKLQW EEEATVNRLQ SNEVTLTLTV PEYSNKRVSR
PVQVYFYVSN GRRKRSPTQS FRFLPVICKE EPLPDSSLRG FPSASATPFG TDMDFSPPRP
PYPSYPHEDP ACETPYLSEG FGYGMPPLYP QTGPPPSYRP GLRMFPETRG TTGCAQPPAV
SFLPRPFPSD PYGGRGSSFS LGLPFSPPAP FRPPPLPASP PLEGPFPSQS DVHPLPAEGY
NKVGPGYGPG EGAPEQEKSR GGYSSGFRDS VPIQGITLEE VSEIIGRDLS GFPAPPGEEP
PA
Records:
Category Evidence Reference
A Mutagenesis Chow CW, Davis RJ., Integration of calcium and cyclic AMP signaling pathways by 14-3-3., [10611249]
End of Record Details