ul_6756----
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PPBD protein
Gene name SRC
Synonyms EC 2.7.10.2; c-Src; p60-Src; pp60c-src
GO annotations GO_component: integral to membrane; membrane
GO_function:ATP binding; nucleotide binding; protein binding [PMID 8681387] [PMID 9763511]; protein-tyrosine kinase activity [PMID 9020193]; SH2 domain binding [PMID 8070403]; SH3/SH2 adaptor activity [PMID 9020193]; transferase activity
GO_process: protein amino acid phosphorylation; protein kinase cascade [PMID 9020193]; signal complex formation [PMID 9924018]
RefSeq accession NP_005408
SwissProt accession P12931
Substrate protein
Gene name AFAP
Synonyms
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_067651
SwissProt accession
Sequence:(RefSeq accession:NP_067651; substrate region highlighted if known)
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61
121
181
241
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361
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481
541
601
661
721
MEELIVELRL FLELLDHEYL TSTVREKKAV ITNILLRIQS SKGFDVKDHA QKQETANSLP
APPQMPLPEI PQPWLPPDSG PPPLPTSSLP EGYYEEAVPL SPGKAPEYIT SNYDSDAMSS
SYESYDEEEE DGKGKKTRHQ WPSEEASMDL VKDAKICAFL LRKKRFGQWT KLLCVIKDTK
LLCYKSSKDQ QPQMELPLQG CNITYIPKDS KKKKHELKIT QQGTDPLVLA VQSKEQAEQW
LKVIKEAYSG CSGPVDSECP PPPSSPVHKA ELEKKLSSER PSSDGEGVVE NGITTCNGKE
QVKRKKSSKS EAKGTVSKVT GKKITKIISL GKKKPSTDEQ TSSAEEDVPT CGYLNVLSNS
RWRERWCRVK DNKLIFHKDR TDLKTHIVSI PLRGCEVIPG LDSKHPLTFR LLRNGQEVAV
LEASSSEDMG RWIGILLAET GSSTDPEALH YDYIDVEMSA SVIQTAKQTF CFMNRRVISA
NPYLGGTSNG YAHPSGTALH YDDVPCINGS LKGKKPPVAS NGVTGKGKTL SSQPKKADPA
AVVKRTGSNA AQYKYGKNRV EADAKRLQTK EEELLKRKEA LRNRLAQLRK ERKDLRAAIE
VNAGRKPQAI LEEKLKQLEE ECRQKEAERV SLELELTEVK ESLKKALAGG VTLGLAIEPK
SGTSSPQSPV FRHRTLENSP ISSCDTSDTE GPVPVNSAAV LKKSQAAPGS SPCRGHVLRK
AKEWELKNGT
Records:
Category Evidence Reference
A Mutagenesis Guappone AC, Weimer T, Flynn DC., Formation of a stable src-AFAP-110 complex through either an amino-terminal or a carboxy-terminal SH2-binding motif, [9655255]
End of Record Details