ul_6811----
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PPBD protein
Gene name SRC
Synonyms EC 2.7.10.2; c-Src; p60-Src; pp60c-src
GO annotations GO_component: integral to membrane; membrane
GO_function:ATP binding; nucleotide binding; protein binding [PMID 8681387] [PMID 9763511]; protein-tyrosine kinase activity [PMID 9020193]; SH2 domain binding [PMID 8070403]; SH3/SH2 adaptor activity [PMID 9020193]; transferase activity
GO_process: protein amino acid phosphorylation; protein kinase cascade [PMID 9020193]; signal complex formation [PMID 9924018]
RefSeq accession NP_005408
SwissProt accession P12931
Substrate protein
Gene name Cav2( Description: caveolin 2. )
Synonyms AI447843
GO annotations GO_component: caveola; caveolar membrane; integral to membrane; integral to plasma membrane; lipid raft; membrane; perinuclear region; plasma membrane
GO_function:protein binding; protein homodimerization activity
GO_process: endocytosis; negative regulation of endothelial cell proliferation; protein oligomerization
RefSeq accession NP_058596
SwissProt accession
Sequence:(RefSeq accession:NP_058596; substrate region highlighted if known)
1
61
121
MGLETEKADV QLFMADDAYS HHSGVDYADP EKYVDSSHDR DPHQLNSHLK LGFEDLIAEP
ETTHSFDKVW ICSHALFEIS KYVMYKFLTV FLAIPLAFIA GILFATLSCL HIWILMPFVK
TCLMVLPSVQ TIWKSVTDVV IGPLCTSVGR SFSSVSMQLS HD
Records:
Category Evidence Reference
A Inference Lee H, Park DS, Wang XB, Scherer PE, Schwartz PE, Lisanti MP., Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1, [12091389]
End of Record Details