ul_6841----
Record details: Hide
PPBD protein
Gene name STAT1
Synonyms
GO annotations GO_component: cytoplasm [PMID 10820245]; nucleus [PMID 10820245]
GO_function:calcium ion binding; hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity [PMID 8608597]; protein binding [PMID 12867595]; signal transducer activity; transcription factor activity [PMID 10820245] [PMID 10848577]
GO_process: caspase activation [PMID 10692450]; I-kappaB kinase/NF-kappaB cascade [PMID 10848577]; intracellular signaling cascade; regulation of progression through cell cycle [PMID 10692450]; regulation of transcription, DNA-dependent; response to virus; STAT protein nuclear translocation; transcription; transcription from RNA polymerase II promoter [PMID 9630226]; tyrosine phosphorylation of STAT protein [PMID 10692450]
RefSeq accession NP_644671
SwissProt accession P42224
Substrate protein
Gene name IFNGR1( Description: interferon gamma receptor 1. )
Synonyms CD119; IFN-gamma R; IFN-gammaR; Ifgr; Ifngr; Nktar
GO annotations GO_component: membrane
GO_function:cytokine binding; receptor activity
GO_process:
RefSeq accession NP_034641
SwissProt accession
GO Pathway:
GO:0007165     signal transduction
Sequence:(RefSeq accession:NP_034641; substrate region highlighted if known)
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MGPQAAAGRM ILLVVLMLSA KVGSGALTST EDPEPPSVPV PTNVLIKSYN LNPVVCWEYQ
NMSQTPIFTV QVKVYSGSWT DSCTNISDHC CNIYEQIMYP DVSAWARVKA KVGQKESDYA
RSKEFLMCLK GKVGPPGLEI RRKKEEQLSV LVFHPEVVVN GESQGTMFGD GSTCYTFDYT
VYVEHNRSGE ILHTKHTVEK EECNETLCEL NISVSTLDSR YCISVDGISS FWQVRTEKSK
DVCIPPFHDD RKDSIWILVV APLTVFTVVI LVFAYWYTKK NSFKRKSIML PKSLLSVVKS
ATLETKPESK YSLVTPHQPA VLESETVICE EPLSTVTAPD SPEAAEQEEL SKETKALEAG
GSTSAMTPDS PPTPTQRRSF SLLSSNQSGP CSLTAYHSRN GSDSGLVGSG SSISDLESLP
NNNSETKMAE HDPPPVRKAP MASGYDKPHM LVDVLVDVGG KESLMGYRLT GEAQELS
Records:
Category Evidence Reference
A Peptide library Greenlund AC, Morales MO, Viviano BL, Yan H, Krolewski J, Schreiber RD., Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process, [7796299]
End of Record Details