ul_6986----
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PPBD protein
Gene name STAT4( Description: signal transducer and activator of transcription 4. )
Synonyms
GO annotations GO_component: nucleus
GO_function:calcium ion binding; signal transducer activity; transcription factor activity [PMID 9284918]
GO_process: intracellular signaling cascade; JAK-STAT cascade [PMID 9284918]; regulation of transcription from RNA polymerase II promoter; transcription
RefSeq accession NP_003142
SwissProt accession Q14765
Substrate protein
Gene name IL12RB2( Description: interleukin 12 receptor, beta 2. )
Synonyms IL-12 receptor beta-2; IL-12R-beta2; RP11-102M16.1
GO annotations GO_component: integral to plasma membrane [PMID 8943050]; membrane
GO_function:interleukin receptor activity [PMID 8943050]; receptor activity
GO_process: cell surface receptor linked signal transduction [PMID 8943050]; positive regulation of cell proliferation [PMID 8943050]
RefSeq accession NP_001550
SwissProt accession Q99665
Sequence:(RefSeq accession:NP_001550; substrate region highlighted if known)
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MAHTFRGCSL AFMFIITWLL IKAKIDACKR GDVTVKPSHV ILLGSTVNIT CSLKPRQGCF
HYSRRNKLIL YKFDRRINFH HGHSLNSQVT GLPLGTTLFV CKLACINSDE IQICGAEIFV
GVAPEQPQNL SCIQKGEQGT VACTWERGRD THLYTEYTLQ LSGPKNLTWQ KQCKDIYCDY
LDFGINLTPE SPESNFTAKV TAVNSLGSSS SLPSTFTFLD IVRPLPPWDI RIKFQKASVS
RCTLYWRDEG LVLLNRLRYR PSNSRLWNMV NVTKAKGRHD LLDLKPFTEY EFQISSKLHL
YKGSWSDWSE SLRAQTPEEE PTGMLDVWYM KRHIDYSRQQ ISLFWKNLSV SEARGKILHY
QVTLQELTGG KAMTQNITGH TSWTTVIPRT GNWAVAVSAA NSKGSSLPTR INIMNLCEAG
LLAPRQVSAN SEGMDNILVT WQPPRKDPSA VQEYVVEWRE LHPGGDTQVP LNWLRSRPYN
VSALISENIK SYICYEIRVY ALSGDQGGCS SILGNSKHKA PLSGPHINAI TEEKGSILIS
WNSIPVQEQM GCLLHYRIYW KERDSNSQPQ LCEIPYRVSQ NSHPINSLQP RVTYVLWMTA
LTAAGESSHG NEREFCLQGK ANWMAFVAPS ICIAIIMVGI FSTHYFQQKV FVLLAALRPQ
WCSREIPDPA NSTCAKKYPI AEEKTQLPLD RLLIDWPTPE DPEPLVISEV LHQVTPVFRH
PPCSNWPQRE KGIQGHQASE KDMMHSASSP PPPRALQAES RQLVDLYKVL ESRGSDPKPE
NPACPWTVLP AGDLPTHDGY LPSNIDDLPS HEAPLADSLE ELEPQHISLS VFPSSSLHPL
TFSCGDKLTL DQLKMRCDSL ML
Records:
Category Evidence Reference
A Peptide library Yao BB, Niu P, Surowy CS, Faltynek CR., Direct interaction of STAT4 with the IL-12 receptor, [10415122]
End of Record Details