ul_7074----
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PPBD protein
Gene name STAT6( Description: signal transducer and activator of transcription 6, interleukin-4 induced. )
Synonyms D12S1644; IL-4-STAT; STAT6B; STAT6C
GO annotations GO_component: nucleus
GO_function:calcium ion binding; signal transducer activity; transcription factor activity [PMID 10747856]
GO_process: intracellular signaling cascade; regulation of transcription from RNA polymerase II promoter [PMID 8810328]; regulation of transcription, DNA-dependent; signal transduction; transcription
RefSeq accession NP_003144
SwissProt accession P42226
Substrate protein
Gene name IL4R( Description: interleukin 4 receptor. )
Synonyms CD124; CD124 antigen; IL-4R-alpha; IL4RA
GO annotations GO_component: integral to plasma membrane [PMID 2307934]; membrane
GO_function:hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-4 receptor activity [PMID 2307934]; protein binding [PMID 8266078]; receptor activity; receptor signaling protein activity [PMID 2307934]
GO_process: immune response [PMID 2307934]; signal transduction [PMID 2307934]
RefSeq accession NP_000409
SwissProt accession P24394
Sequence:(RefSeq accession:NP_000409; substrate region highlighted if known)
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MGWLCSGLLF PVSCLVLLQV ASSGNMKVLQ EPTCVSDYMS ISTCEWKMNG PTNCSTELRL
LYQLVFLLSE AHTCIPENNG GAGCVCHLLM DDVVSADNYT LDLWAGQQLL WKGSFKPSEH
VKPRAPGNLT VHTNVSDTLL LTWSNPYPPD NYLYNHLTYA VNIWSENDPA DFRIYNVTYL
EPSLRIAAST LKSGISYRAR VRAWAQCYNT TWSEWSPSTK WHNSYREPFE QHLLLGVSVS
CIVILAVCLL CYVSITKIKK EWWDQIPNPA RSRLVAIIIQ DAQGSQWEKR SRGQEPAKCP
HWKNCLTKLL PCFLEHNMKR DEDPHKAAKE MPFQGSGKSA WCPVEISKTV LWPESISVVR
CVELFEAPVE CEEEEEVEEE KGSFCASPES SRDDFQEGRE GIVARLTESL FLDLLGEENG
GFCQQDMGES CLLPPSGSTS AHMPWDEFPS AGPKEAPPWG KEQPLHLEPS PPASPTQSPD
NLTCTETPLV IAGNPAYRSF SNSLSQSPCP RELGPDPLLA RHLEEVEPEM PCVPQLSEPT
TVPQPEPETW EQILRRNVLQ HGAAAAPVSA PTSGYQEFVH AVEQGGTQAS AVVGLGPPGE
AGYKAFSSLL ASSAVSPEKC GFGASSGEEG YKPFQDLIPG CPGDPAPVPV PLFTFGLDRE
PPRSPQSSHL PSSSPEHLGL EPGEKVEDMP KPPLPQEQAT DPLVDSLGSG IVYSALTCHL
CGHLKQCHGQ EDGGQTPVMA SPCCGCCCGD RSSPPTTPLR APDPSPGGVP LEASLCPASL
APSGISEKSK SSSSFHPAPG NAQSSSQTPK IVNFVSVGPT YMRVS
Records:
Category Evidence Reference
A Inference Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M, McKnight SL., An interleukin-4-induced transcription factor: IL-4 Stat, [8085155]
End of Record Details