ul_7097----
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PPBD protein
Gene name SYK( Description: spleen tyrosine kinase. )
Synonyms EC 2.7.10.2; Spleen tyrosine kinase
GO annotations GO_component: cytoplasm; T cell receptor complex [PMID 8176201]
GO_function:ATP binding; integrin binding [PMID 12885943]; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding [PMID 8627166] [PMID 9280292] [PMID 12885943]; transferase activity
GO_process: cell proliferation [PMID 10963601]; integrin-mediated signaling pathway [PMID 12885943]; intracellular signaling cascade; leukocyte adhesion [PMID 12885943]; neutrophil chemotaxis [PMID 12885943]; organ morphogenesis [PMID 7477352]; protein amino acid phosphorylation [PMID 8163536]; protein complex assembly [PMID 8163536]
RefSeq accession NP_003168
SwissProt accession P43405
Substrate protein
Gene name gp60 SU( Description: p18. )
Synonyms
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_056899
SwissProt accession
Sequence:(RefSeq accession:NP_056899; substrate region highlighted if known)
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MPKERRSRRR PQPIIRWVSL TLTLLALCQP IQTWRCSLSL GNQQWMTTYN QEAKFSISID
QILEAHNQSP FCPRSPRYTL DFVNGYPKIY WPPPQGRRRF GARAMVTYDC EPRCPYVGAD
HFDCPHWDNA SQADQGSFYV NHQILFLHLK QCHGIFTLTW EIWGYDPLIT FSLHKIPDPP
QPDFPQLNSD WVPSVRSWAL LLNQTARAFP DCAICWEPSP PWAPEILVYN KTISGSGPGL
ALPDAQIFWV NTSLFNTTQG WHHPSQRLLF NVSQGNALLL PPISLVNLST VSSAPPTRVR
RSPVAALTLG LALSVGLTGI NVAVSALSHQ RLTSLIHVLE QDQQRLITAI NQTHYNLLNV
ASVVAQNRRG LDWLYIRLGF QSLCPTINEP CCFLRIQNDS IIRLGDLQPL SQRVSTDWQW
PWNWDLGLTA WVRETIHSVL SLFLLALFLL FLAPCLIKCL TSRLLKLLRQ APHFPEISFP
PKPDSDYQAL LPSAPEIYSH LSPTKPDYIN LRPCP
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details