ul_725----
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PPBD protein
Gene name YWHAQ( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide. )
Synonyms 14-3-3; 14-3-3 protein T-cell; 14-3-3 protein tau; 1C5; HS1; HS1 protein
GO annotations GO_component:
GO_function:protein domain specific binding; protein kinase C inhibitor activity
GO_process: exocytosis; regulation of progression through cell cycle
RefSeq accession NP_006817
SwissProt accession P27348
Substrate protein
Gene name YAP1( Description: Yes-associated protein 1, 65kDa. )
Synonyms YAP; YAP2; YAP65
GO annotations GO_component:
GO_function:protein binding [PMID 7782338]
GO_process:
RefSeq accession NP_006097
SwissProt accession P46937
Sequence:(RefSeq accession:NP_006097; substrate region highlighted if known)
1
61
121
181
241
301
361
421
MDPGQQPPPQ PAPQGQGQPP SQPPQGQGPP SGPGQPAPAA TQAAPQAPPA GHQIVHVRGD
SETDLEALFN AVMNPKTANV PQTVPMRLRK LPDSFFKPPE PKSHSRQAST DAGTAGALTP
QHVRAHSSPA SLQLG
AVSPG TLTPTGVVSG PAATPTAQHL RQSSFEIPDD VPLPAGWEMA
KTSSGQRYFL NHIDQTTTWQ DPRKAMLSQM NVTAPTSPPV QQNMMNSASA MNQRISQSAP
VKQPPPLAPQ SPQGGVMGGS NSNQQQQMRL QQLQMEKERL RLKQQELLRQ VRPQELALRS
QLPTLEQDGG TQNPVSSPGM SQELRTMTTN SSDPFLNSGT YHSRDESTDS GLSMSSYSVP
RTPDDFLNSV DEMDTGDTIN QSTLPSQQNR FPDYLEAIPG TNVDLGTLEG DGMNIEGEEL
MPSLQEALSS DILNDMESVL AATKLDKESF LTWL
Records:
Category Evidence Reference
A Mutagenesis Basu S, Totty NF, Irwin MS, Sudol M, Downward J., Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis., [12535517]
End of Record Details