ul_7288----
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PPBD protein
Gene name VAV1( Description: vav 1 oncogene. )
Synonyms VAV
GO annotations GO_component: intracellular; nucleus
GO_function:diacylglycerol binding; metal ion binding; protein binding [PMID 10394361]; Rho guanyl-nucleotide exchange factor activity; transcription factor activity [PMID 2477241]; zinc ion binding
GO_process: intracellular signaling cascade; regulation of Rho protein signal transduction
RefSeq accession NP_005419
SwissProt accession P15498
Substrate protein
Gene name Mapk4( Description: mitogen-activated protein kinase 4. )
Synonyms A330097D03Rik; Erk3; Prkm4; p63Mapk
GO annotations GO_component:
GO_function:kinase activity; nucleotide binding; protein serine/threonine kinase activity; transferase activity
GO_process: cell cycle
RefSeq accession NP_766220
SwissProt accession
Sequence:(RefSeq accession:NP_766220; substrate region highlighted if known)
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MAEKGDCIAS VYGYDLGGRF IDFQPLGFGV NGLVLSATDS RACRKVAVKK IVLSDARSMK
HALREIKIIR RLDHDNIVKV YEVLGPKGSD LQGELFKFSV AYIVQEYMET DLACLLEQGT
LTEDHAKLFM YQLLRGLKYI HSANVLHRDL KPANIFISTE DLVLKIGDFG LARIVDQHYS
HKGYLSEGLV TKWYRSPRLL LSPNNYTKAI DMWAAGCILA EMLTGKMLFA GAHELEQMQL
ILDTIPVVRE EDKEELLRVM PSFVSSTWEV KRPLRKLLPD VNSEAIDFLE KILTFNPMDR
LTAEMGLQHP YMSPYSCPED EPTSQHPFRI EDEIDDIVLM AASQSQLSNW DRYPVSLSSD
LEWRPDRCQD ASEVQRDPRA GSTPLAEDVQ VDPRKDSQSS SERFLEQSHS SMERAFEADY
GRSCDYKVGS PSYLDKLLWR DNKPHHYSEP KLILDLSHWK QAASAPPRAA VAADPVSRED
EPASLFLEIA QWVKSTQSGS ERASPPPDAP EPRLSASPPG HPTPIDGGAS PQFDLDVFIS
RALKLCTKPE DLPENKLGDL NGACISEHPG DLVQTEAFSK ERW
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details