ul_78----
Record details: Hide
PPBD protein
Gene name SFN( Description: stratifin. )
Synonyms Epithelial cell marker protein 1; Stratifin; YWHAS
GO annotations GO_component: cytoplasm [PMID 10767298]; extracellular space [PMID 8515476]
GO_function:protein domain specific binding; protein kinase C inhibitor activity [PMID 8515476]
GO_process: cell proliferation [PMID 10767298]; negative regulation of protein kinase activity [PMID 8515476]; regulation of progression through cell cycle [PMID 10767298]; signal transduction [PMID 8515476]
RefSeq accession NP_006133
SwissProt accession P31947
Substrate protein
Gene name ING1
Synonyms ING1Lp; Inhibitor of growth 1-like protein; p32; p33ING2
GO annotations GO_component: nucleus [PMID 10866301]
GO_function:metal ion binding; protein binding; zinc ion binding
GO_process: cell cycle; negative regulation of cell growth [PMID 8944021]; negative regulation of cell proliferation [PMID 8944021]; negative regulation of progression through cell cycle; regulation of transcription, DNA-dependent
RefSeq accession NP_937862
SwissProt accession Q9H160
Sequence:(RefSeq accession:NP_937862; substrate region highlighted if known)
1
61
121
181
241
MLSPANGEQL HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDECYERFSR
ETDGAQKRRM LHCVQRALIR SQELGDEKIQ IVSQMVELVE NRTRQVDSHV ELFEAQQELG
DTAGNSGKAG ADRPKGEAAA QADKPNSKRS RRQRNNENRE NASSNHDHDD GASGTPKEKK
AKTSKKKKRS KAKAEREASP ADLPIDPNEP TYCLCNQVSY GEMIGCDNDE CPIEWFHFSC
VGLNHKPKGK WYCPKCRGEN EKTMDKALEK SKKERAYNR
Records:
Category Evidence Reference
A Mutagenesis Gong W, Russell M, Suzuki K, Riabowol K., Subcellular targeting of p33ING1b by phosphorylation-dependent 14-3-3 binding regulates p21WAF1 expression., [16581770]
End of Record Details