ul_82----
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PPBD protein
Gene name SFN( Description: stratifin. )
Synonyms Epithelial cell marker protein 1; Stratifin; YWHAS
GO annotations GO_component: cytoplasm [PMID 10767298]; extracellular space [PMID 8515476]
GO_function:protein domain specific binding; protein kinase C inhibitor activity [PMID 8515476]
GO_process: cell proliferation [PMID 10767298]; negative regulation of protein kinase activity [PMID 8515476]; regulation of progression through cell cycle [PMID 10767298]; signal transduction [PMID 8515476]
RefSeq accession NP_006133
SwissProt accession P31947
Substrate protein
Gene name RELA( Description: v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian). )
Synonyms MGC131774; NFKB3
GO annotations GO_component: cytoplasm [PMID 3140380]; nucleus [PMID 3140380]; transcription factor complex [PMID 12048232]
GO_function:identical protein binding [PMID 9437432]; NF-kappaB binding [PMID 8441377]; phosphate binding [PMID 10521409]; protein kinase binding [PMID 10521409] [PMID 15465828]; protein N-terminus binding [PMID 7739562]; RNA polymerase II transcription factor activity, enhancer binding [PMID 3091258]; signal transducer activity [PMID 12761501]; transcription factor activity
GO_process: activation of NF-kappaB transcription factor [PMID 15790681]; anti-apoptosis [PMID 10747850]; cellular defense response [PMID 8717528]; cytokine and chemokine mediated signaling pathway [PMID 15876188]; defense response to virus [PMID 8717528]; inflammatory response [PMID 12924514]; positive regulation of I-kappaB kinase/NF-kappaB cascade [PMID 12761501]; regulation of transcription, DNA-dependent; response to organic substance [PMID 10747850]; response to UV-B [PMID 15616591]
RefSeq accession NP_068810
SwissProt accession Q04206
Sequence:(RefSeq accession:NP_068810; substrate region highlighted if known)
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MDELFPLIFP AEPAQASGPY VEIIEQPKQR GMRFRYKCEG RSAGSIPGER STDTTKTHPT
IKINGYTGPG TVRISLVTKD PPHRPHPHEL VGKDCRDGFY EAELCPDRCI HSFQNLGIQC
VKKRDLEQAI SQRIQTNNNP FQVPIEEQRG DYDLNAVRLC FQVTVRDPSG RPLRLPPVLP
HPIFDNRAPN TAELKICRVN RNSGSCLGGD EIFLLCDKVQ KEDIEVYFTG PGWEARGSFS
QADVHRQVAI VFRTPPYADP SLQAPVRVSM QLRRPSDREL SEPMEFQYLP DTDDRHRIEE
KRKRTYETFK SIMKKSPFSG PTDPRPPPRR IAVPSRSSAS VPKPAPQPYP FTSSLSTINY
DEFPTMVFPS GQISQASALA PAPPQVLPQA PAPAPAPAMV SALAQAPAPV PVLAPGPPQA
VAPPAPKPTQ AGEGTLSEAL LQLQFDDEDL GALLGNSTDP AVFTDLASVD NSEFQQLLNQ
GIPVAPHTTE PMLMEYPEAI TRLVTGAQRP PDPAPAPLGA PGLPNGLLSG DEDFSSIADM
DFSALLSQIS S
Records:
Category Evidence Reference
A Inference Aguilera C, Fernández-Majada V, Inglés-Esteve J, Rodilla V, Bigas A, Espinosa L., Efficient nuclear export of p65-IkappaBalpha complexes requires 14-3-3 proteins., [16931600]
End of Record Details