ul_8529----
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PPBD protein
Gene name PIN1( Description: protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1. )
Synonyms DOD; EC 5.2.1.8; PPIase Pin1; Rotamase Pin1; UBL5
GO annotations GO_component: nucleus [PMID 8606777]
GO_function:isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding [PMID 11470801]
GO_process: cell cycle; protein folding; regulation of mitosis [PMID 10391244]
RefSeq accession NP_006212
SwissProt accession Q13526
Substrate protein
Gene name CDC25C
Synonyms Dual specificity phosphatase Cdc25C; EC 3.1.3.48
GO annotations GO_component: intracellular; nucleus
GO_function:hydrolase activity; protein tyrosine phosphatase activity [PMID 11078813]
GO_process: cell cycle; cell division; cell proliferation [PMID 11139144]; protein amino acid dephosphorylation; regulation of cyclin-dependent protein kinase activity [PMID 11139144]; regulation of mitosis [PMID 1828290]; traversing start control point of mitotic cell cycle [PMID 2195549]
RefSeq accession NP_001781
SwissProt accession P30307
Sequence:(RefSeq accession:NP_001781; substrate region highlighted if known)
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MSTELFSSTR EEGSSGSGPS FRSNQRKMLN LLLERDTSFT VCPDVPRTPV GKFLGDSANL
SILSGGTPKC CLDLSNLSSG EITATQLTTS ADLDETGHLD SSGLQEVHLA GMNHDQHLMK
CSPAQLLCST PNGLDRGHRK RDAMCSSSAN KENDNGNLVD SEMKYLGSPI TTVPKLDKNP
NLGEDQAEEI SDELMEFSLK DQEAKVSRSG LYRSPSMPEN LNRPRLKQVE KFKDNTIPDK
VKKKYFSGQG KLRKGLCLKK TVSLCDITIT QMLEEDSNQG HLIGDFSKVC ALPTVSGKHQ
DLKYVNPETV AALLSGKFQG LIEKFYVIDC RYPYEYLGGH IQGALNLYSQ EELFNFFLKK
PIVPLDTQKR IIIVFHCEFS SERGPRMCRC LREEDRSLNQ YPALYYPELY ILKGGYRDFF
PEYMELCEPQ SYCPMHHQDH KTELLRCRSQ SKVQEGERQL REQIALLVKD MSP
Records:
Category Evidence Reference
A Peptide library Lu PJ, Zhou XZ, Shen M, Lu KP., Human ubiquitin-protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes., [10037602]
End of Record Details