ul_8602----
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PPBD protein
Gene name PIN1( Description: protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1. )
Synonyms DOD; EC 5.2.1.8; PPIase Pin1; Rotamase Pin1; UBL5
GO annotations GO_component: nucleus [PMID 8606777]
GO_function:isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding [PMID 11470801]
GO_process: cell cycle; protein folding; regulation of mitosis [PMID 10391244]
RefSeq accession NP_006212
SwissProt accession Q13526
Substrate protein
Gene name SLC9A3R1( Description: solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1. )
Synonyms EBP50; NHERF; NHERF-1; NHERF1; Na(+)/H(+) exchange regulatory cofactor NHE-RF; Regulatory cofactor of Na(+)/H(+) exchanger; Sodium-hydrogen exchanger regulatory factor 1; Solute carrier family 9 isoform 3 regulatory factor 1
GO annotations GO_component: actin cytoskeleton [PMID 9430655]
GO_function:beta-2 adrenergic receptor binding [PMID 9560162]; protein binding [PMID 11285285] [PMID 12471024]; sodium:hydrogen antiporter regulator activity [PMID 9560162]
GO_process: protein complex assembly [PMID 9430655]; Wnt receptor signaling pathway
RefSeq accession NP_004243
SwissProt accession Q28619
GO Pathway:
GO:0007049     cell cycle
GO:0007088     regulation of mitosis
Sequence:(RefSeq accession:NP_004243; substrate region highlighted if known)
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MSADAAAGAP LPRLCCLEKG PNGYGFHLHG EKGKLGQYIR LVEPGSPAEK AGLLAGDRLV
EVNGENVEKE THQQVVSRIR AALNAVRLLV VDPETDEQLQ KLGVQVREEL LRAQEAPGQA
EPPAAAEVQG AGNENEPREA DKSHPEQREL RPRLCTMKKG PSGYGFNLHS DKSKPGQFIR
SVDPDSPAEA SGLRAQDRIV EVNGVCMEGK QHGDVVSAIR AGGDETKLLV VDRETDEFFK
KCRVIPSQEH LNGPLPVPFT NGEIQKENSR EALAEAALES PRPALVRSAS SDTSEELNSQ
DSPPKQDSTA PSSTSSSDPI LDFNISLAMA KERAHQKRSS KRAPQMDWSK KNELFSNL
Records:
Category Evidence Reference
A Inference He J, Lau AG, Yaffe MB, Hall RA., Phosphorylation and cell cycle-dependent regulation of Na+/H+ exchanger regulatory factor-1 by Cdc2 kinase., [11533036]
End of Record Details