ul_8644----
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PPBD protein
Gene name PIN1( Description: protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1. )
Synonyms DOD; EC 5.2.1.8; PPIase Pin1; Rotamase Pin1; UBL5
GO annotations GO_component: nucleus [PMID 8606777]
GO_function:isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding [PMID 11470801]
GO_process: cell cycle; protein folding; regulation of mitosis [PMID 10391244]
RefSeq accession NP_006212
SwissProt accession Q13526
Substrate protein
Gene name ZBTB16( Description: zinc finger and BTB domain containing 16. )
Synonyms PLZF; Promyelocytic leukemia zinc finger protein; ZNF145; Zinc finger protein 145; Zinc finger protein PLZF
GO annotations GO_component: intracellular; nuclear speck [PMID 8541544]; nucleus [PMID 9294197]; transcriptional repressor complex [PMID 12802276]
GO_function:DNA binding [PMID 9294197]; metal ion binding; protein homodimerization activity [PMID 8622986]; specific transcriptional repressor activity [PMID 12802276]; zinc ion binding
GO_process: apoptosis [PMID 9294197]; central nervous system development [PMID 8541544]; mesonephros development [PMID 8541544]; myeloid cell differentiation [PMID 9294197]; negative regulation of myeloid cell differentiation [PMID 8541544]; negative regulation of transcription, DNA-dependent [PMID 12802276]; transcription
RefSeq accession NP_005997
SwissProt accession Q05516
Sequence:(RefSeq accession:NP_005997; substrate region highlighted if known)
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MDLTKMGMIQ LQNPSHPTGL LCKANQMRLA GTLCDVVIMV DSQEFHAHRT VLACTSKMFE
ILFHRNSQHY TLDFLSPKTF QQILEYAYTA TLQAKAEDLD DLLYAAEILE IEYLEEQCLK
MLETIQASDD NDTEATMADG GAEEEEDRKA RYLKNIFISK HSSEESGYAS VAGQSLPGPM
VDQSPSVSTS FGLSAMSPTK AAVDSLMTIG QSLLQGTLQP PAGPEEPTLA GGGRHPGVAE
VKTEMMQVDE VPSQDSPGAA ESSISGGMGD KVEERGKEGP GTPTRSSVIT SARELHYGRE
ESAEQVPPPA EAGQAPTGRP EHPAPPPEKH LGIYSVLPNH KADAVLSMPS SVTSGLHVQP
ALAVSMDFST YGGLLPQGFI QRELFSKLGE LAVGMKSESR TIGEQCSVCG VELPDNEAVE
QHRKLHSGMK TYGCELCGKR FLDSLRLRMH LLAHSAGAKA FVCDQCGAQF SKEDALETHR
QTHTGTDMAV FCLLCGKRFQ AQSALQQHME VHAGVRSYIC SECNRTFPSH TALKRHLRSH
TGDHPYECEF CGSCFRDEST LKSHKRIHTG EKPYECNGCG KKFSLKHQLE THYRVHTGEK
PFECKLCHQR SRDYSAMIKH LRTHNGASPY QCTICTEYCP SLSSMQKHMK GHKPEEIPPD
WRIEKTYLYL CYV
Records:
Category Evidence Reference
A Peptide library Otte L, Wiedemann U, Schlegel B, Pires JR, Beyermann M, Schmieder P, Krause G, Volkmer-Engert R, Schneider-Mergener J, Oschkinat H., WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains., [12592019]
End of Record Details