ul_8649----
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PPBD protein
Gene name PIN1( Description: protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1. )
Synonyms DOD; EC 5.2.1.8; PPIase Pin1; Rotamase Pin1; UBL5
GO annotations GO_component: nucleus [PMID 8606777]
GO_function:isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding [PMID 11470801]
GO_process: cell cycle; protein folding; regulation of mitosis [PMID 10391244]
RefSeq accession NP_006212
SwissProt accession Q13526
Substrate protein
Gene name NTRK3
Synonyms EC 2.7.10.1; GP145-TrkC; Neurotrophic tyrosine kinase receptor type 3; Trk-C; TrkC tyrosine kinase
GO annotations GO_component: integral to plasma membrane [PMID 7806211]; membrane
GO_function:ATP binding; kinase activity; neurotrophin binding [PMID 7806211]; nucleotide binding; protein-tyrosine kinase activity; receptor activity; transferase activity; transmembrane receptor protein tyrosine kinase activity
GO_process: cell differentiation; nervous system development; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway [PMID 7806211]
RefSeq accession NP_001012338
SwissProt accession Q16288
Sequence:(RefSeq accession:NP_001012338; substrate region highlighted if known)
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MDVSLCPAKC SFWRIFLLGS VWLDYVGSVL ACPANCVCSK TEINCRRPDD GNLFPLLEGQ
DSGNSNGNAS INITDISRNI TSIHIENWRS LHTLNAVDME LYTGLQKLTI KNSGLRSIQP
RAFAKNPHLR YINLSSNRLT TLSWQLFQTL SLRELQLEQN FFNCSCDIRW MQLWQEQGEA
KLNSQNLYCI NADGSQLPLF RMNISQCDLP EISVSHVNLT VREGDNAVIT CNGSGSPLPD
VDWIVTGLQS INTHQTNLNW TNVHAINLTL VNVTSEDNGF TLTCIAENVV GMSNASVALT
VYYPPRVVSL EEPELRLEHC IEFVVRGNPP PTLHWLHNGQ PLRESKIIHV EYYQEGEISE
GCLLFNKPTH YNNGNYTLIA KNPLGTANQT INGHFLKEPF PESTDNFILF DEVSPTPPIT
VTHKPEEDTF GVSIAVGLAA FACVLLVVLF VMINKYGRRS KFGMKGPVAV ISGEEDSASP
LHHINHGITT PSSLDAGPDT VVIGMTRIPV IENPQYFRQG HNCHKPDTYV QHIKRRDIVL
KRELGEGAFG KVFLAECYNL SPTKDKMLVA VKALKDPTLA ARKDFQREAE LLTNLQHEHI
VKFYGVCGDG DPLIMVFEYM KHGDLNKFLR AHGPDAMILV DGQPRQAKGE LGLSQMLHIA
SQIASGMVYL ASQHFVHRDL ATRNCLVGAN LLVKIGDFGM SRDVYSTDYY RLFNPSGNDF
CIWCEVGGHT MLPIRWMPPE SIMYRKFTTE SDVWSFGVIL WEIFTYGKQP WFQLSNTEVI
ECITQGRVLE RPRVCPKEVY DVMLGCWQRE PQQRLNIKEI YKILHALGKA TPIYLDILG
Records:
Category Evidence Reference
A Peptide library Otte L, Wiedemann U, Schlegel B, Pires JR, Beyermann M, Schmieder P, Krause G, Volkmer-Engert R, Schneider-Mergener J, Oschkinat H., WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains., [12592019]
End of Record Details