ul_8656----
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PPBD protein
Gene name PIN1( Description: protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1. )
Synonyms DOD; EC 5.2.1.8; PPIase Pin1; Rotamase Pin1; UBL5
GO annotations GO_component: nucleus [PMID 8606777]
GO_function:isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding [PMID 11470801]
GO_process: cell cycle; protein folding; regulation of mitosis [PMID 10391244]
RefSeq accession NP_006212
SwissProt accession Q13526
Substrate protein
Gene name KIF11( Description: kinesin family member 11. )
Synonyms EG5; HKSP; KNSL1; Kinesin-like protein 1; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; TRIP-5; TRIP5; Thyroid receptor-interacting protein 5
GO annotations GO_component: kinesin complex [PMID 8548803]; microtubule; microtubule associated complex; spindle microtubule [PMID 14718566]; spindle pole [PMID 14718566]
GO_function:ATP binding; microtubule motor activity [PMID 8548803]; nucleotide binding
GO_process: cell cycle; cell division; microtubule-based movement; mitosis [PMID 8548803]; mitotic spindle organization and biogenesis [PMID 8548803]; spindle pole body organization and biogenesis [PMID 14718566]
RefSeq accession NP_004514
SwissProt accession P52732
Sequence:(RefSeq accession:NP_004514; substrate region highlighted if known)
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1021
MASQPNSSAK KKEEKGKNIQ VVVRCRPFNL AERKASAHSI VECDPVRKEV SVRTGGLADK
SSRKTYTFDM VFGASTKQID VYRSVVCPIL DEVIMGYNCT IFAYGQTGTG KTFTMEGERS
PNEEYTWEED PLAGIIPRTL HQIFEKLTDN GTEFSVKVSL LEIYNEELFD LLNPSSDVSE
RLQMFDDPRN KRGVIIKGLE EITVHNKDEV YQILEKGAAK RTTAATLMNA YSSRSHSVFS
VTIHMKETTI DGEELVKIGK LNLVDLAGSE NIGRSGAVDK RAREAGNINQ SLLTLGRVIT
ALVERTPHVP YRESKLTRIL QDSLGGRTRT SIIATISPAS LNLEETLSTL EYAHRAKNIL
NKPEVNQKLT KKALIKEYTE EIERLKRDLA AAREKNGVYI SEENFRVMSG KLTVQEEQIV
ELIEKIGAVE EELNRVTELF MDNKNELDQC KSDLQNKTQE LETTQKHLQE TKLQLVKEEY
ITSALESTEE KLHDAASKLL NTVEETTKDV SGLHSKLDRK KAVDQHNAEA QDIFGKNLNS
LFNNMEELIK DGSSKQKAML EVHKTLFGNL LSSSVSALDT ITTVALGSLT SIPENVSTHV
SQIFNMILKE QSLAAESKTV LQELINVLKT DLLSSLEMIL SPTVVSILKI NSQLKHIFKT
SLTVADKIED QKKELDGFLS ILCNNLHELQ ENTICSLVES QKQCGNLTED LKTIKQTHSQ
ELCKLMNLWT ERFCALEEKC ENIQKPLSSV QENIQQKSKD IVNKMTFHSQ KFCADSDGFS
QELRNFNQEG TKLVEESVKH SDKLNGNLEK ISQETEQRCE SLNTRTVYFS EQWVSSLNER
EQELHNLLEV VSQCCEASSS DITEKSDGRK AAHEKQHNIF LDQMTIDEDK LIAQNLELNE
TIKIGLTKLN CFLEQDLKLD IPTGTTPQRK SYLYPSTLVR TEPREHLLDQ LKRKQPELLM
MLNCSENNKE ETIPDVDVEE AVLGQYTEEP LSQEPSVDAG VDCSSIGGVP FFQHKKSHGK
DKENRGINTL ERSKVEETTE HLVTKSRLPL RAQINL
Records:
Category Evidence Reference
A Peptide library Otte L, Wiedemann U, Schlegel B, Pires JR, Beyermann M, Schmieder P, Krause G, Volkmer-Engert R, Schneider-Mergener J, Oschkinat H., WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains., [12592019]
End of Record Details