ul_8657----
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PPBD protein
Gene name PIN1( Description: protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1. )
Synonyms DOD; EC 5.2.1.8; PPIase Pin1; Rotamase Pin1; UBL5
GO annotations GO_component: nucleus [PMID 8606777]
GO_function:isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding [PMID 11470801]
GO_process: cell cycle; protein folding; regulation of mitosis [PMID 10391244]
RefSeq accession NP_006212
SwissProt accession Q13526
Substrate protein
Gene name RBL2( Description: retinoblastoma-like 2 (p130). )
Synonyms 130 kDa retinoblastoma-associated protein; FLJ26459; P130; PRB2; RBR-2; Rb2
GO annotations GO_component: nucleus
GO_function:DNA binding; protein binding [PMID 16286473]
GO_process: cell cycle; negative regulation of progression through cell cycle; regulation of lipid kinase activity [PMID 16286473]; regulation of transcription, DNA-dependent; transcription
RefSeq accession NP_005602
SwissProt accession Q08999
Sequence:(RefSeq accession:NP_005602; substrate region highlighted if known)
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MPSGGDQSPP PPPPPPAAAA SDEEEEDDGE AEDAAPSAES PTPQIQQRFD ELCSRLNMDE
AARPEAWDSY RSMSESYTLE GNDLHWLACA LYVACRKSVP TVSKGTVEGN YVSLTRILKC
SEQSLIEFFN KMKKWEDMAN LPPHFRERTE RLERNFTVSA VIFKKYEPIF QDIFKYPQEE
QPRQQRGRKQ RRQPCTVSEI FHFCWVLFIY AKGNFPMISD DLVNSYHLLL CALDLVYGNA
LQCSNRKELV NPNFKGLSED FHAKDSKPSS DPPCIIEKLC SLHDGLVLEA KGIKEHFWKP
YIRKLYEKKL LKGKEENLTG FLEPGNFGES FKAINKAYEE YVLSVGNLDE RIFLGEDAEE
EIGTLSRCLN AGSGTETAER VQMKNILQQH FDKSKALRIS TPLTGVRYIK ENSPCVTPVS
TATHSLSRLH TMLTGLRNAP SEKLEQILRT CSRDPTQAIA NRLKEMFEIY SQHFQPDEDF
SNCAKEIASK HFRFAEMLYY KVLESVIEQE QKRLGDMDLS GILEQDAFHR SLLACCLEVV
TFSYKPPGNF PFITEIFDVP LYHFYKVIEV FIRAEDGLCR EVVKHLNQIE EQILDHLAWK
PESPLWEKIR DNENRVPTCE EVMPPQNLER ADEICIAGSP LTPRRVTEVR ADTGGLGRSI
TSPTTLYDRY SSPPASTTRR RLFVENDSPS DGGTPGRMPP QPLVNAVPVQ NVSGETVSVT
PVPGQTLVTM ATATVTANNG QTVTIPVQGI ANENGGITFF PVQVNVGGQA QAVTGSIQPL
SAQALAGSLS SQQVTGTTLQ VPGQVAIQQI SPGGQQQKQG QSVTSSSNRP RKTSSLSLFF
RKVYHLAAVR LRDLCAKLDI SDELRKKIWT CFEFSIIQCP ELMMDRHLDQ LLMCAIYVMA
KVTKEDKSFQ NIMRCYRTQP QARSQVYRSV LIKGKRKRRN SGSSDSRSHQ NSPTELNKDR
TSRDSSPVMR SSSTLPVPQP SSAPPTPTRL TGANSDMEEE ERGDLIQFYN NIYIKQIKTF
AMKYSQANMD APPLSPYPFV RTGSPRRIQL SQNHPVYISP HKNETMLSPR EKIFYYFSNS
PSKRLREINS MIRTGETPTK KRGILLEDGS ESPAKRICPE NHSALLRRLQ DVANDRGSH
Records:
Category Evidence Reference
A Peptide library Otte L, Wiedemann U, Schlegel B, Pires JR, Beyermann M, Schmieder P, Krause G, Volkmer-Engert R, Schneider-Mergener J, Oschkinat H., WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains., [12592019]
End of Record Details