ul_8692----
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PPBD protein
Gene name PIN1( Description: protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1. )
Synonyms DOD; EC 5.2.1.8; PPIase Pin1; Rotamase Pin1; UBL5
GO annotations GO_component: nucleus [PMID 8606777]
GO_function:isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding [PMID 11470801]
GO_process: cell cycle; protein folding; regulation of mitosis [PMID 10391244]
RefSeq accession NP_006212
SwissProt accession Q13526
Substrate protein
Gene name FOS( Description: v-fos FBJ murine osteosarcoma viral oncogene homolog. )
Synonyms Cellular oncogene fos; G0/G1 switch regulatory protein 7; c-fos
GO annotations GO_component: nucleus [PMID 9443941]
GO_function:protein dimerization activity; sequence-specific DNA binding; specific RNA polymerase II transcription factor activity [PMID 10918580]; transcription factor activity
GO_process: DNA methylation [PMID 9888853]; inflammatory response [PMID 9443941]; regulation of transcription from RNA polymerase II promoter [PMID 10918580]
RefSeq accession NP_005243
SwissProt accession P01100
GO Pathway:
GO:0006357     regulation of transcription from RNA polymerase¢ò promoter
Sequence:(RefSeq accession:NP_005243; substrate region highlighted if known)
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MMFSGFNADY EASSSRCSSA SPAGDSLSYY HSPADSFSSM GSPVNAQDFC TDLAVSSANF
IPTVTAISTS PDLQWLVQPA LVSSVAPSQT RAPHPFGVPA PSAGAYSRAG VVKTMTGGRA
QSIGRRGKVE QLSPEEEEKR RIRRERNKMA AAKCRNRRRE LTDTLQAETD QLEDEKSALQ
TEIANLLKEK EKLEFILAAH RPACKIPDDL GFPEEMSVAS LDLTGGLPEV ATPESEEAFT
LPLLNDPEPK PSVEPVKSIS SMELKTEPFD DFLFPASSRP SGSETARSVP DMDLSGSFYA
ADWEPLHSGS LGMGPMATEL EPLCTPVVTC TPSCTAYTSS FVFTYPEADS FPSCAAAHRK
GSSSNEPSSD SLSSPTLLAL
Records:
Category Evidence Reference
A Mutagenesis Monje P, Hernández-Losa J, Lyons RJ, Castellone MD, Gutkind JS., Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1., [16123044]
End of Record Details