ul_88----
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PPBD protein
Gene name SFN( Description: stratifin. )
Synonyms Epithelial cell marker protein 1; Stratifin; YWHAS
GO annotations GO_component: cytoplasm [PMID 10767298]; extracellular space [PMID 8515476]
GO_function:protein domain specific binding; protein kinase C inhibitor activity [PMID 8515476]
GO_process: cell proliferation [PMID 10767298]; negative regulation of protein kinase activity [PMID 8515476]; regulation of progression through cell cycle [PMID 10767298]; signal transduction [PMID 8515476]
RefSeq accession NP_006133
SwissProt accession P31947
Substrate protein
Gene name HDAC7A( Description: histone deacetylase 7A. )
Synonyms DKFZP586J0917; HDAC7
GO annotations GO_component: cytoplasm [PMID 12711221]; histone deacetylase complex [PMID 12711221]; nucleus [PMID 12711221]
GO_function:histone deacetylase activity [PMID 12711221]; hydrolase activity; specific transcriptional repressor activity [PMID 12711221]; transcription factor binding [PMID 12711221]
GO_process: B cell differentiation [PMID 12711221]; chromatin modification [PMID 12711221]; inflammatory response [PMID 12711221]; negative regulation of striated muscle development [PMID 12711221]; nervous system development [PMID 12711221]; regulation of progression through cell cycle [PMID 12711221]; regulation of transcription, DNA-dependent; transcription
RefSeq accession NP_056216
SwissProt accession Q8WUI4
Sequence:(RefSeq accession:NP_056216; substrate region highlighted if known)
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MDLRVGQRPP VEPPPEPTLL ALQRPQRLHH HLFLAGLQQQ RSVEPMRLSM DTPMPELQVG
PQEQELRQLL HKDKSKRSAV ASSVVKQKLA EVILKKQQAA LERTVHPNSP GIPYRTLEPL
ETEGATRSML SSFLPPVPSL PSDPPEHFPL RKTVSEPNLK LRYKPKKSLE RRKNPLLRKE
SAPPSLRRRP AETLGDSSPS SSSTPASGCS SPNDSEHGPN PILGSEALLG QRLRLQETSV
APFALPTVSL LPAITLGLPA PARADSDRRT HPTLGPRGPI LGSPHTPLFL PHGLEPEAGG
TLPSRLQPIL LLDPSGSHAP LLTVPGLGPL PFHFAQSLMT TERLSGSGLH WPLSRTRSEP
LPPSATAPPP PGPMQPRLEQ LKTHVQVIKR SAKPSEKPRL RQIPSAEDLE TDGGGPGQVV
DDGLEHRELG HGQPEARGPA PLQQHPQVLL WEQQRLAGRL PRGSTGDTVL LPLAQGGHRP
LSRAQSSPAA PASLSAPEPA SQARVLSSSE TPARTLPFTT GLIYDSVMLK HQCSCGDNSR
HPEHAGRIQS IWSRLQERGL RSQCECLRGR KASLEELQSV HSERHVLLYG TNPLSRLKLD
NGKLAGLLAQ RMFVMLPCGG VGVDTDTIWN ELHSSNAARW AAGSVTDLAF KVASRELKNG
FAVVRPPGHH ADHSTAMGFC FFNSVAIACR QLQQQSKASK ILIVDWDVHH GNGTQQTFYQ
DPSVLYISLH RHDDGNFFPG SGAVDEVGAG SGEGFNVNVA WAGGLDPPMG DPEYLAAFRI
VVMPIAREFS PDLVLVSAGF DAAEGHPAPL GGYHVSAKCF GYMTQQLMNL AGGAVVLALE
GGHDLTAICD ASEACVAALL GNRVDPLSEE GWKQKPNLNA IRSLEAVIRV HSKYWGCMQR
LASCPDSWVP RVPGADKEEV EAVTALASLS VGILAEDRPS EQLVEEEEPM NL
Records:
Category Evidence Reference
A Inference Dequiedt F, Martin M, Von Blume J, Vertommen D, Lecomte E, Mari N, Heinen MF, Bachmann M, Twizere JC, Huang MC, Rider MH, Piwnica-Worms H, Seufferlein T, Kettmann R., New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases., [16980613]
End of Record Details