ul_9----
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PPBD protein
Gene name SFN( Description: stratifin. )
Synonyms Epithelial cell marker protein 1; Stratifin; YWHAS
GO annotations GO_component: cytoplasm [PMID 10767298]; extracellular space [PMID 8515476]
GO_function:protein domain specific binding; protein kinase C inhibitor activity [PMID 8515476]
GO_process: cell proliferation [PMID 10767298]; negative regulation of protein kinase activity [PMID 8515476]; regulation of progression through cell cycle [PMID 10767298]; signal transduction [PMID 8515476]
RefSeq accession NP_006133
SwissProt accession P31947
Substrate protein
Gene name CD74
Synonyms CD74 antigen; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33
GO annotations GO_component: integral to membrane [PMID 6324166]; intracellular [PMID 12782713]; membrane
GO_function:cytokine binding [PMID 12782713]; identical protein binding [PMID 12782713]; MHC class II protein binding [PMID 10981873]
GO_process: antigen processing and presentation of endogenous antigen [PMID 10981873]; cell proliferation [PMID 12782713]; immune response; immunoglobulin mediated immune response; intracellular protein transport; negative regulation of apoptosis [PMID 12782713]; prostaglandin biosynthesis [PMID 12782713]; protein complex assembly; protein folding; regulation of macrophage activation [PMID 12782713]; signal transduction [PMID 12782713]; T cell selection [PMID 10981873]
RefSeq accession NP_001020330
SwissProt accession P04233
GO Pathway:
GO:0009966     regulation of signal transduction
Sequence:(RefSeq accession:NP_001020330; substrate region highlighted if known)
1
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MHRRRSRSCR EDQKPVMDDQ RDLISNNEQL PMLGRRPGAP ESKCSRGALY TGFSILVTLL
LAGQATTAYF LYQQQGRLDK LTVTSQNLQL ENLRMKLPKP PKPVSKMRMA TPLLMQALPM
GALPQGPMQN ATKYGNMTED HVMHLLQNAD PLKVYPPLKG SFPENLRHLK NTMETIDWKV
FESWMHHWLL FEMSRHSLEQ KPTDAPPKVL TKCQEEVSHI PAVHPGSFRP KCDENGNYLP
LQCYGSIGYC WCVFPNGTEV PNTRSRGHHN CSESLELEDP SSGLGVTKQD LGPVPM
Records:
Category Evidence Reference
A Mutagenesis Kuwana T, Peterson PA, Karlsson L., Exit of major histocompatibility complex class II-invariant chain p35 complexes from the endoplasmic reticulum is modulated by phosphorylation., [9448284]
End of Record Details